| SP | McQuillan, G.McQuillan, George >> | 22 | 1907 | R | 91 | 19 | 19 | 5 | 5 | 4.33 | .331 | 1.42 | 8.4 | 4.4 | 4.3 | 116.1 | 108 | 60 | 56 | 8 | 57 | 56 | 1 | 0 | 0 | 0 | 10 | 8 | 4 | 4.61 |
| SP | McDowell, J.McDowell, Jack >> | 21 | 1987 | R | 86 | 19 | 19 | 9 | 6 | 5.13 | .315 | 1.34 | 9.8 | 2.3 | 3.8 | 114.0 | 124 | 81 | 65 | 10 | 29 | 48 | 2 | 0 | 0 | 0 | 9 | 4 | 0 | 4.17 |
| SP | Koufax, S.Koufax, Sandy >> | 28 | 1963 | L | 70 | 18 | 18 | 7 | 5 | 3.82 | .314 | 1.33 | 9.8 | 2.2 | 5.6 | 110.2 | 120 | 50 | 47 | 15 | 27 | 68 | 1 | 0 | 0 | 0 | 10 | 5 | 2 | 4.41 |
| SP | Schupp, F.Schupp, Ferdie >> | 25 | 1916 | L | 85 | 13 | 13 | 6 | 2 | 3.12 | .275 | 1.10 | 6.5 | 3.4 | 4.7 | 69.1 | 50 | 25 | 24 | 5 | 26 | 36 | 0 | 0 | 0 | 0 | 7 | 3 | 0 | 4.16 |
| SP | Cushman, E.Cushman, Ed >> | 32 | 1884 | L | 100 | 14 | 14 | 8 | 3 | 3.50 | .284 | 1.17 | 8.6 | 1.9 | 8.4 | 97.2 | 93 | 42 | 38 | 10 | 21 | 90 | 4 | 0 | 0 | 0 | 8 | 2 | 0 | 3.20 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 95 | 43 | 0 | 2 | 5 | 6.37 | .349 | 1.54 | 11.0 | 2.9 | 9.0 | 41.0 | 50 | 29 | 29 | 4 | 13 | 41 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 3.44 |
| RP | Furbush, C.Furbush, Charlie >> | 29 | 2015 | L | 86 | 33 | 0 | 3 | 1 | 2.61 | .260 | 0.97 | 5.4 | 3.3 | 7.3 | 38.0 | 23 | 13 | 11 | 4 | 14 | 31 | 0 | 1 | 1 | 0 | 0 | 3 | 7 | 4.08 |
| RP | Sanchez, A.Sanchez, Aaron >> | 21 | 2014 | R | 81 | 22 | 0 | 1 | 1 | 4.81 | .305 | 1.32 | 6.0 | 6.0 | 5.6 | 24.1 | 16 | 13 | 13 | 2 | 16 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 4.83 |
| RP | de los Santos, V.de los Santos, Valerio >> | 26 | 1998 | L | 80 | 18 | 0 | 0 | 2 | 4.96 | .310 | 1.35 | 10.7 | 1.7 | 6.2 | 16.1 | 19 | 11 | 9 | 1 | 3 | 11 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 3.00 |
| SU | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 67 | 29 | 0 | 0 | 1 | 4.55 | .310 | 1.31 | 9.3 | 2.8 | 8.1 | 29.2 | 30 | 19 | 15 | 1 | 9 | 26 | 0 | 3 | 5 | 0 | 0 | 1 | 1 | 2.69 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 78 | 2 | 1 | 0 | 0 | 13.50 | .385 | 1.88 | 22.5 | 0.0 | 18.0 | 2.2 | 5 | 4 | 4 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -1.00 |
| SP | Sweeney, C.Sweeney, Charlie >> | 21 | 1884 | R | 72 | 13 | 0 | 1 | 2 | 4.52 | .303 | 1.27 | 9.7 | 1.9 | 4.7 | 63.2 | 68 | 36 | 32 | 4 | 13 | 33 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3.49 |