| SP | Scherzer, M.Scherzer, Max >> | 37 | 2021 | R | 79 | 19 | 19 | 5 | 12 | 6.11 | .346 | 1.53 | 10.7 | 3.1 | 7.5 | 95.2 | 113 | 67 | 65 | 12 | 33 | 79 | 0 | 0 | 0 | 0 | 5 | 6 | 1 | 4.21 |
| SP | McKenzie, T.McKenzie, Triston >> | 22 | 2020 | R | 71 | 18 | 18 | 2 | 6 | 4.46 | .335 | 1.49 | 9.5 | 4.0 | 8.3 | 76.2 | 80 | 48 | 38 | 8 | 34 | 70 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 3.95 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 61 | 15 | 13 | 4 | 9 | 6.24 | .376 | 1.81 | 12.0 | 4.5 | 7.8 | 70.2 | 93 | 50 | 49 | 11 | 35 | 61 | 0 | 0 | 0 | 0 | 6 | 0 | 1 | 4.80 |
| CL | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 76 | 40 | 0 | 1 | 1 | 3.89 | .285 | 1.14 | 9.0 | 1.4 | 8.3 | 39.1 | 39 | 19 | 17 | 5 | 6 | 36 | 0 | 16 | 1 | 0 | 0 | 2 | 0 | 3.44 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 43 | 43 | 0 | 2 | 0 | 2.97 | .295 | 1.24 | 6.5 | 4.8 | 7.7 | 60.2 | 43 | 22 | 20 | 1 | 32 | 51 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.17 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 26 | 45 | 0 | 7 | 1 | 3.61 | .280 | 1.11 | 6.9 | 3.1 | 7.8 | 52.1 | 40 | 22 | 21 | 4 | 18 | 45 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 3.48 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 19 | 36 | 0 | 3 | 0 | 3.17 | .253 | 0.93 | 6.9 | 1.5 | 9.6 | 48.1 | 37 | 17 | 17 | 6 | 8 | 51 | 0 | 0 | 0 | 0 | 0 | 4 | 3 | 3.25 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 33 | 16 | 1 | 3 | 2 | 4.60 | .327 | 1.42 | 9.5 | 3.3 | 4.0 | 78.1 | 82 | 48 | 40 | 15 | 29 | 35 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 5.83 |
| SP | Parnell, R.Parnell, Roy >> | 28 | 1932 | R | 59 | 16 | 0 | 3 | 2 | 3.80 | .312 | 1.31 | 7.3 | 4.7 | 4.7 | 21.1 | 17 | 9 | 9 | 2 | 11 | 11 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.90 |