| SP | Snell, B.Snell, Blake † >> | 25 | 2018 | L | 88 | 18 | 18 | 10 | 4 | 3.07 | .287 | 1.20 | 6.6 | 4.3 | 8.8 | 114.1 | 83 | 39 | 39 | 10 | 54 | 111 | 0 | 0 | 0 | 0 | 12 | 1 | 11 | 3.64 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 19 | 19 | 5 | 8 | 4.04 | .295 | 1.22 | 8.0 | 3.1 | 9.8 | 129.1 | 114 | 59 | 58 | 22 | 44 | 140 | 2 | 0 | 0 | 1 | 11 | 4 | 3 | 4.16 |
| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 57 | 16 | 13 | 6 | 4 | 4.02 | .320 | 1.39 | 9.1 | 3.5 | 8.7 | 100.2 | 101 | 48 | 45 | 10 | 39 | 97 | 0 | 0 | 0 | 0 | 7 | 2 | 4 | 3.59 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 17 | 17 | 5 | 8 | 4.12 | .275 | 1.12 | 8.1 | 2.0 | 10.9 | 111.1 | 100 | 51 | 51 | 15 | 25 | 134 | 1 | 0 | 0 | 0 | 9 | 2 | 2 | 3.07 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 84 | 46 | 0 | 3 | 3 | 3.53 | .293 | 1.23 | 8.8 | 2.3 | 11.0 | 58.2 | 57 | 23 | 23 | 8 | 15 | 71 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.17 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 26 | 0 | 1 | 3 | 4.18 | .288 | 1.21 | 5.5 | 5.5 | 8.0 | 28.0 | 17 | 13 | 13 | 4 | 17 | 25 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 4.89 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 22 | 0 | 0 | 0 | 3.97 | .244 | 0.97 | 4.5 | 4.5 | 5.3 | 22.2 | 11 | 10 | 10 | 3 | 11 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.09 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 3 | 0 | 0 | 0 | 0.00 | .263 | 1.07 | 6.8 | 4.5 | 6.8 | 4.2 | 3 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SU | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 92 | 29 | 0 | 1 | 2 | 3.77 | .256 | 1.03 | 6.4 | 2.9 | 9.0 | 31.0 | 22 | 14 | 13 | 5 | 10 | 31 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.06 |
| CL | Street, H.Street, Huston † >> | 29 | 2012 | R | 96 | 35 | 0 | 2 | 3 | 3.92 | .269 | 1.08 | 5.5 | 4.2 | 10.4 | 39.0 | 24 | 19 | 17 | 4 | 18 | 45 | 0 | 17 | 3 | 0 | 0 | 1 | 1 | 3.49 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 85 | 14 | 5 | 5 | 2 | 6.98 | .346 | 1.59 | 11.0 | 3.3 | 7.8 | 58.0 | 71 | 45 | 45 | 10 | 21 | 50 | 0 | 0 | 0 | 0 | 2 | 0 | 1 | 4.60 |