| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 14 | 14 | 7 | 5 | 3.90 | .306 | 1.29 | 9.1 | 2.5 | 9.3 | 90.0 | 91 | 41 | 39 | 13 | 25 | 93 | 1 | 0 | 0 | 0 | 8 | 3 | 2 | 3.74 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 14 | 14 | 4 | 6 | 4.15 | .306 | 1.31 | 8.9 | 3.0 | 8.4 | 84.2 | 83 | 43 | 39 | 11 | 28 | 78 | 0 | 0 | 0 | 0 | 8 | 1 | 2 | 3.88 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 88 | 13 | 13 | 3 | 4 | 5.71 | .287 | 1.18 | 8.2 | 2.5 | 4.9 | 64.2 | 58 | 41 | 41 | 13 | 18 | 35 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 5.48 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 69 | 13 | 13 | 4 | 6 | 4.40 | .323 | 1.37 | 8.8 | 3.5 | 5.9 | 90.0 | 88 | 46 | 44 | 11 | 35 | 59 | 3 | 0 | 0 | 0 | 7 | 6 | 3 | 4.64 |
| RP | Chapman, A.Chapman, Aroldis >> | 24 | 2012 | L | 88 | 35 | 0 | 2 | 1 | 3.81 | .304 | 1.31 | 7.3 | 4.5 | 11.8 | 26.0 | 21 | 11 | 11 | 5 | 13 | 34 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 4.38 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 19 | 0 | 1 | 1 | 5.60 | .321 | 1.42 | 9.0 | 4.2 | 12.2 | 17.2 | 17 | 11 | 11 | 2 | 8 | 23 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.24 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 14 | 0 | 2 | 0 | 3.65 | .327 | 1.38 | 10.5 | 2.3 | 12.8 | 12.1 | 14 | 5 | 5 | 1 | 3 | 17 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 2.25 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 9 | 0 | 0 | 0 | 4.15 | .170 | 0.62 | 4.2 | 1.4 | 8.3 | 13.0 | 6 | 6 | 6 | 2 | 2 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.62 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 68 | 11 | 0 | 1 | 0 | 4.26 | .309 | 1.34 | 9.8 | 3.0 | 7.5 | 12.2 | 13 | 6 | 6 | 4 | 4 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.67 |
| CL | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 25 | 0 | 3 | 5 | 2.92 | .321 | 1.38 | 6.4 | 6.4 | 9.0 | 24.2 | 17 | 8 | 8 | 1 | 17 | 24 | 0 | 14 | 0 | 0 | 0 | 1 | 3 | 3.79 |
| SP | Harvey, M.Harvey, Matt >> | 24 | 2013 | R | 77 | 12 | 1 | 3 | 0 | 5.09 | .333 | 1.48 | 10.8 | 2.5 | 9.8 | 46.0 | 55 | 27 | 26 | 8 | 13 | 50 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 4.00 |