| SP | Hernandez, C.Hernandez, Carlos $ >> | 27 | 2002 | L | 81 | 16 | 16 | 4 | 6 | 4.35 | .312 | 1.30 | 9.6 | 2.1 | 5.4 | 89.0 | 95 | 45 | 43 | 12 | 21 | 53 | 0 | 0 | 0 | 0 | 9 | 5 | 2 | 4.44 |
| SP | Lackey, J.Lackey, John $ >> | 29 | 2002 | R | 71 | 16 | 16 | 3 | 11 | 4.98 | .314 | 1.32 | 9.6 | 2.3 | 4.7 | 97.2 | 104 | 59 | 54 | 18 | 25 | 51 | 4 | 0 | 0 | 0 | 7 | 5 | 1 | 5.29 |
| SP | Santana, J.Santana, Johan $ >> | 28 | 2000 | L | 68 | 16 | 16 | 2 | 4 | 2.99 | .295 | 1.18 | 8.7 | 2.0 | 6.1 | 69.1 | 67 | 24 | 23 | 5 | 15 | 47 | 0 | 0 | 0 | 0 | 0 | 5 | 1 | 3.45 |
| SP | Halladay, R.Halladay, Roy # $ >> | 30 | 1999 | R | 44 | 16 | 16 | 3 | 9 | 4.84 | .285 | 1.16 | 7.9 | 2.6 | 5.6 | 89.1 | 78 | 48 | 48 | 13 | 26 | 55 | 0 | 0 | 0 | 0 | 6 | 3 | 0 | 4.64 |
| RP | Zumaya, J.Zumaya, Joel $ >> | 23 | 2006 | R | 83 | 47 | 0 | 0 | 3 | 4.25 | .362 | 1.62 | 9.8 | 5.1 | 8.3 | 48.2 | 52 | 23 | 23 | 7 | 27 | 44 | 0 | 0 | 2 | 0 | 0 | 4 | 3 | 5.00 |
| RP | Romero, J.Romero, J.C. $ >> | 31 | 2002 | L | 81 | 50 | 0 | 0 | 2 | 8.24 | .366 | 1.65 | 11.1 | 3.9 | 10.8 | 39.1 | 48 | 36 | 36 | 15 | 17 | 47 | 0 | 0 | 2 | 0 | 0 | 3 | 2 | 7.13 |
| RP | Rincon, J.Rincon, Juan $ >> | 28 | 2003 | R | 80 | 40 | 0 | 3 | 5 | 5.18 | .336 | 1.44 | 9.2 | 3.9 | 5.8 | 48.2 | 49 | 30 | 28 | 7 | 21 | 31 | 0 | 0 | 2 | 0 | 0 | 4 | 4 | 5.17 |
| RP | Santos, V.Santos, Victor >> | 31 | 2001 | R | 70 | 32 | 0 | 3 | 1 | 5.89 | .351 | 1.58 | 10.2 | 4.1 | 4.1 | 44.1 | 50 | 29 | 29 | 6 | 20 | 20 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.36 |
| CL | Timlin, M.Timlin, Mike >> | 41 | 2007 | R | 52 | 32 | 0 | 0 | 3 | 4.37 | .281 | 1.17 | 8.0 | 2.6 | 4.6 | 35.0 | 31 | 18 | 17 | 4 | 10 | 18 | 0 | 15 | 3 | 0 | 0 | 0 | 0 | 4.31 |
| SP | Verlander, J.Verlander, Justin $ >> | 24 | 2006 | R | 35 | 20 | 0 | 5 | 0 | 4.43 | .339 | 1.49 | 9.5 | 3.9 | 6.7 | 67.0 | 71 | 33 | 33 | 11 | 29 | 50 | 0 | 0 | 0 | 0 | 0 | 3 | 1 | 5.07 |