| SP | Hernandez, C.Hernandez, Carlos $ >> | 27 | 2002 | L | 81 | 33 | 33 | 6 | 16 | 5.00 | .326 | 1.41 | 9.9 | 2.8 | 6.2 | 176.1 | 194 | 105 | 98 | 30 | 55 | 122 | 0 | 0 | 0 | 0 | 15 | 7 | 3 | 4.89 |
| SP | Lackey, J.Lackey, John # $ >> | 29 | 2002 | R | 71 | 33 | 33 | 9 | 16 | 4.86 | .302 | 1.27 | 9.0 | 2.5 | 5.9 | 198.1 | 198 | 112 | 107 | 32 | 54 | 130 | 5 | 0 | 0 | 1 | 15 | 6 | 7 | 4.70 |
| SP | Santana, J.Santana, Johan $ >> | 28 | 2000 | L | 68 | 32 | 32 | 2 | 10 | 4.43 | .309 | 1.29 | 9.7 | 1.9 | 5.8 | 134.0 | 144 | 68 | 66 | 14 | 29 | 86 | 0 | 0 | 0 | 0 | 2 | 7 | 4 | 3.88 |
| SP | Halladay, R.Halladay, Roy # $ >> | 30 | 1999 | R | 44 | 32 | 32 | 8 | 16 | 4.60 | .308 | 1.30 | 8.2 | 3.5 | 5.6 | 174.0 | 158 | 97 | 89 | 27 | 68 | 109 | 0 | 0 | 0 | 0 | 11 | 6 | 0 | 5.04 |
| RP | Zumaya, J.Zumaya, Joel $ >> | 23 | 2006 | R | 83 | 94 | 0 | 5 | 4 | 4.56 | .354 | 1.60 | 9.3 | 5.2 | 9.2 | 104.2 | 107 | 55 | 53 | 11 | 60 | 106 | 0 | 0 | 2 | 0 | 0 | 5 | 4 | 4.21 |
| RP | Romero, J.Romero, J.C. $ >> | 31 | 2002 | L | 81 | 101 | 0 | 3 | 5 | 6.53 | .358 | 1.61 | 10.9 | 3.7 | 9.6 | 81.1 | 98 | 61 | 59 | 20 | 33 | 86 | 0 | 1 | 4 | 0 | 0 | 5 | 7 | 5.49 |
| RP | Rincon, J.Rincon, Juan # $ >> | 28 | 2003 | R | 80 | 77 | 0 | 5 | 6 | 4.01 | .313 | 1.32 | 8.5 | 3.4 | 7.0 | 107.2 | 101 | 50 | 48 | 13 | 41 | 83 | 0 | 1 | 5 | 0 | 0 | 5 | 5 | 4.32 |
| RP | Santos, V.Santos, Victor >> | 31 | 2001 | R | 70 | 59 | 0 | 6 | 3 | 6.52 | .364 | 1.70 | 10.2 | 5.2 | 5.3 | 89.2 | 101 | 65 | 65 | 12 | 51 | 52 | 0 | 1 | 1 | 0 | 0 | 2 | 0 | 5.37 |
| CL | Timlin, M.Timlin, Mike >> | 41 | 2007 | R | 52 | 61 | 0 | 1 | 5 | 3.56 | .299 | 1.26 | 8.2 | 3.3 | 4.7 | 65.2 | 59 | 27 | 26 | 7 | 24 | 34 | 0 | 29 | 7 | 0 | 0 | 1 | 0 | 4.51 |
| SP | Verlander, J.Verlander, Justin $ >> | 24 | 2006 | R | 35 | 40 | 0 | 9 | 1 | 5.17 | .343 | 1.53 | 10.2 | 3.5 | 6.8 | 132.1 | 150 | 76 | 76 | 22 | 52 | 99 | 0 | 0 | 0 | 0 | 0 | 5 | 3 | 4.96 |