| SP | Zito, B.Zito, Barry # $ >> | 29 | 2000 | L | 100 | 38 | 38 | 19 | 9 | 4.29 | .299 | 1.23 | 8.2 | 2.9 | 7.0 | 260.0 | 238 | 131 | 124 | 37 | 83 | 201 | 5 | 0 | 0 | 0 | 19 | 11 | 3 | 4.39 |
| SP | Harden, R.Harden, Rich $ >> | 26 | 2003 | R | 89 | 38 | 38 | 18 | 12 | 3.68 | .275 | 1.09 | 7.1 | 2.7 | 6.4 | 242.1 | 191 | 101 | 99 | 27 | 72 | 172 | 1 | 0 | 0 | 0 | 27 | 13 | 7 | 4.08 |
| SP | Lyon, B.Lyon, Brandon $ >> | 28 | 2001 | R | 88 | 36 | 36 | 15 | 14 | 4.57 | .302 | 1.27 | 8.5 | 3.0 | 6.0 | 246.1 | 231 | 129 | 125 | 34 | 83 | 163 | 6 | 0 | 0 | 1 | 20 | 6 | 0 | 4.56 |
| SP | Lilly, T.Lilly, Ted # $ >> | 31 | 2002 | L | 88 | 33 | 33 | 8 | 10 | 5.07 | .315 | 1.35 | 9.5 | 2.7 | 6.6 | 165.0 | 174 | 103 | 93 | 26 | 49 | 121 | 0 | 0 | 0 | 0 | 8 | 5 | 5 | 4.56 |
| SP | Hudson, T.Hudson, Tim # $ >> | 32 | 1999 | R | 81 | 33 | 32 | 8 | 14 | 4.82 | .325 | 1.40 | 9.6 | 3.0 | 10.4 | 209.1 | 224 | 122 | 112 | 32 | 70 | 241 | 3 | 0 | 0 | 1 | 15 | 8 | 3 | 3.80 |
| RP | Osuna, A.Osuna, Antonio $ >> | 34 | 1996 | R | 88 | 89 | 0 | 6 | 4 | 3.32 | .277 | 1.13 | 8.0 | 2.2 | 7.1 | 97.2 | 86 | 37 | 36 | 11 | 24 | 77 | 0 | 1 | 3 | 0 | 0 | 2 | 3 | 3.69 |
| RP | Heredia, F.Heredia, Felix $ >> | 32 | 1997 | L | 89 | 87 | 0 | 3 | 1 | 4.61 | .328 | 1.42 | 8.0 | 4.9 | 8.0 | 70.1 | 62 | 37 | 36 | 4 | 38 | 62 | 0 | 2 | 1 | 0 | 0 | 3 | 1 | 3.73 |
| RP | Reyes, D.Reyes, Dennys $ >> | 30 | 2006 | L | 80 | 44 | 0 | 1 | 1 | 3.20 | .248 | 0.97 | 6.7 | 2.1 | 6.9 | 39.1 | 29 | 14 | 14 | 8 | 9 | 30 | 0 | 1 | 0 | 0 | 0 | 1 | 1 | 4.90 |
| CL | Street, H.Street, Huston # $ >> | 24 | 2005 | R | 94 | 73 | 0 | 9 | 12 | 4.38 | .288 | 1.20 | 8.4 | 2.4 | 8.5 | 76.0 | 71 | 38 | 37 | 8 | 20 | 72 | 0 | 41 | 7 | 0 | 0 | 1 | 0 | 3.30 |
| SP | Kendrick, K.Kendrick, Kyle >> | 23 | 2007 | R | 34 | 28 | 0 | 2 | 3 | 4.89 | .348 | 1.56 | 10.9 | 3.2 | 5.3 | 110.1 | 133 | 62 | 60 | 16 | 39 | 65 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 4.91 |