| SP | Lowry, N.Lowry, Noah $ >> | 27 | 2004 | L | 71 | 35 | 35 | 13 | 11 | 4.41 | .305 | 1.26 | 8.8 | 2.6 | 7.8 | 218.1 | 213 | 115 | 107 | 35 | 63 | 190 | 4 | 0 | 0 | 3 | 18 | 11 | 3 | 4.36 |
| SP | Ohka, T.Ohka, Tomokazu $ >> | 31 | 2000 | R | 63 | 34 | 34 | 14 | 14 | 3.83 | .289 | 1.20 | 8.0 | 2.8 | 6.6 | 218.1 | 194 | 101 | 93 | 23 | 68 | 161 | 1 | 0 | 0 | 1 | 19 | 4 | 1 | 3.89 |
| SP | James, C.James, Chuck # >> | 26 | 2006 | L | 62 | 34 | 34 | 5 | 8 | 4.69 | .325 | 1.41 | 9.1 | 3.7 | 5.3 | 174.2 | 175 | 96 | 91 | 25 | 72 | 102 | 0 | 0 | 0 | 0 | 10 | 5 | 4 | 5.02 |
| SP | Thurman, M.Thurman, Mike # $ >> | 34 | 1998 | R | 55 | 33 | 33 | 12 | 10 | 4.38 | .321 | 1.38 | 9.3 | 3.1 | 6.1 | 176.2 | 182 | 90 | 86 | 19 | 61 | 119 | 0 | 0 | 0 | 0 | 12 | 8 | 3 | 4.23 |
| SP | Schilling, C.Schilling, Curt $ >> | 41 | 2004 | R | 54 | 31 | 31 | 12 | 13 | 4.20 | .309 | 1.32 | 9.3 | 2.6 | 6.1 | 212.0 | 219 | 108 | 99 | 24 | 61 | 143 | 0 | 0 | 0 | 0 | 14 | 4 | 3 | 4.04 |
| CL | Papelbon, J.Papelbon, Jonathan $ >> | 27 | 2006 | R | 99 | 68 | 0 | 5 | 12 | 5.53 | .310 | 1.32 | 9.7 | 2.3 | 9.7 | 68.1 | 73 | 43 | 42 | 16 | 17 | 73 | 0 | 32 | 9 | 0 | 0 | 2 | 0 | 4.75 |
| SU | Kim, B.Kim, Byung-Hyun $ >> | 28 | 2003 | R | 87 | 58 | 0 | 1 | 4 | 6.86 | .370 | 1.73 | 12.7 | 2.9 | 6.3 | 63.0 | 89 | 49 | 48 | 9 | 20 | 44 | 0 | 7 | 6 | 0 | 0 | 2 | 2 | 4.51 |
| RP | Delcarmen, M.Delcarmen, Manny $ >> | 25 | 2007 | R | 78 | 85 | 0 | 6 | 3 | 4.79 | .305 | 1.31 | 7.6 | 4.2 | 6.6 | 107.0 | 90 | 63 | 57 | 17 | 50 | 78 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.04 |
| RP | Okajima, H.Okajima, Hideki $ >> | 32 | 2007 | L | 77 | 82 | 0 | 9 | 1 | 3.43 | .299 | 1.26 | 8.0 | 3.3 | 5.7 | 97.0 | 86 | 43 | 37 | 8 | 36 | 61 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 3.99 |
| RP | Cordero, C.Cordero, Chad $ >> | 25 | 2004 | R | 74 | 64 | 0 | 2 | 4 | 3.00 | .284 | 1.18 | 7.4 | 3.2 | 8.5 | 84.0 | 69 | 31 | 28 | 6 | 30 | 79 | 0 | 0 | 2 | 0 | 0 | 1 | 4 | 3.15 |
| RP | Betancourt, R.Betancourt, Rafael $ >> | 32 | 2003 | R | 71 | 57 | 0 | 3 | 2 | 2.76 | .287 | 1.18 | 6.4 | 4.2 | 7.5 | 62.0 | 44 | 21 | 19 | 4 | 29 | 52 | 0 | 1 | 1 | 0 | 0 | 2 | 2 | 3.66 |
| SP | Thompson, J.Thompson, Justin >> | 34 | 1996 | L | 51 | 9 | 1 | 3 | 1 | 3.70 | .330 | 1.48 | 10.1 | 3.4 | 6.8 | 24.1 | 27 | 11 | 10 | 0 | 9 | 18 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.63 |