| SP | Lowry, N.Lowry, Noah $ >> | 27 | 2004 | L | 71 | 17 | 17 | 4 | 7 | 5.38 | .323 | 1.37 | 9.6 | 2.7 | 8.4 | 97.0 | 104 | 59 | 58 | 18 | 29 | 90 | 2 | 0 | 0 | 2 | 6 | 6 | 2 | 4.64 |
| SP | Ohka, T.Ohka, Tomokazu $ >> | 31 | 2000 | R | 63 | 16 | 16 | 8 | 7 | 4.12 | .290 | 1.23 | 8.5 | 2.6 | 7.3 | 102.2 | 96 | 51 | 47 | 12 | 30 | 83 | 0 | 0 | 0 | 0 | 9 | 0 | 0 | 3.78 |
| SP | Thurman, M.Thurman, Mike # $ >> | 34 | 1998 | R | 55 | 16 | 16 | 8 | 5 | 4.34 | .313 | 1.34 | 8.9 | 3.2 | 6.1 | 87.0 | 86 | 46 | 42 | 13 | 31 | 59 | 0 | 0 | 0 | 0 | 7 | 2 | 1 | 4.72 |
| SP | Schilling, C.Schilling, Curt $ >> | 41 | 2004 | R | 54 | 15 | 15 | 4 | 7 | 4.46 | .321 | 1.39 | 10.2 | 2.3 | 6.6 | 101.0 | 114 | 54 | 50 | 11 | 26 | 74 | 0 | 0 | 0 | 0 | 6 | 3 | 2 | 3.81 |
| CL | Papelbon, J.Papelbon, Jonathan $ >> | 27 | 2006 | R | 99 | 34 | 0 | 1 | 7 | 5.85 | .307 | 1.30 | 9.3 | 2.5 | 10.1 | 32.1 | 33 | 22 | 21 | 6 | 9 | 36 | 0 | 15 | 2 | 0 | 0 | 1 | 0 | 4.13 |
| SU | Kim, B.Kim, Byung-Hyun $ >> | 28 | 2003 | R | 87 | 27 | 0 | 0 | 1 | 8.59 | .413 | 2.05 | 15.5 | 3.1 | 5.0 | 29.1 | 50 | 29 | 28 | 4 | 10 | 16 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.93 |
| RP | Delcarmen, M.Delcarmen, Manny $ >> | 25 | 2007 | R | 78 | 42 | 0 | 4 | 2 | 4.18 | .299 | 1.28 | 7.4 | 4.2 | 7.1 | 51.2 | 42 | 28 | 24 | 6 | 24 | 40 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.37 |
| RP | Okajima, H.Okajima, Hideki $ >> | 32 | 2007 | L | 77 | 40 | 0 | 2 | 1 | 2.93 | .274 | 1.11 | 7.2 | 2.7 | 7.2 | 46.0 | 37 | 19 | 15 | 7 | 14 | 37 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.35 |
| RP | Cordero, C.Cordero, Chad $ >> | 25 | 2004 | R | 74 | 29 | 0 | 1 | 0 | 2.08 | .235 | 0.90 | 5.4 | 2.7 | 7.5 | 43.1 | 26 | 10 | 10 | 2 | 13 | 36 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 2.91 |
| RP | Betancourt, R.Betancourt, Rafael $ >> | 32 | 2003 | R | 71 | 26 | 0 | 1 | 1 | 3.10 | .287 | 1.14 | 6.2 | 4.0 | 7.4 | 29.0 | 20 | 11 | 10 | 3 | 13 | 24 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.24 |
| SP | Thompson, J.Thompson, Justin >> | 34 | 1996 | L | 51 | 6 | 0 | 2 | 0 | 4.50 | .375 | 1.80 | 11.7 | 4.5 | 8.1 | 10.0 | 13 | 5 | 5 | 0 | 5 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.70 |