| SP | Verlander, J.Verlander, Justin >> | 29 | 2012 | R | 97 | 17 | 17 | 9 | 7 | 4.36 | .299 | 1.26 | 8.5 | 2.9 | 8.7 | 119.2 | 112 | 58 | 58 | 19 | 39 | 115 | 2 | 0 | 0 | 0 | 8 | 2 | 1 | 4.18 |
| SP | Patton, T.Patton, Troy # >> | 22 | 2007 | L | 71 | 17 | 17 | 1 | 6 | 4.98 | .325 | 1.41 | 9.3 | 3.6 | 5.8 | 68.2 | 70 | 44 | 38 | 12 | 27 | 44 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 5.28 |
| SP | Fister, D.Fister, Doug # >> | 28 | 2012 | R | 50 | 17 | 17 | 3 | 8 | 5.21 | .327 | 1.44 | 10.5 | 2.5 | 7.1 | 102.0 | 119 | 61 | 59 | 18 | 28 | 80 | 1 | 0 | 0 | 0 | 8 | 2 | 1 | 4.61 |
| SP | Sanchez, A.Sanchez, Anibal >> | 28 | 2012 | R | 27 | 10 | 2 | 2 | 2 | 4.93 | .350 | 1.56 | 10.9 | 3.4 | 7.1 | 34.2 | 41 | 19 | 19 | 6 | 13 | 27 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.03 |
| SP | Scherzer, M.Scherzer, Max # >> | 28 | 2012 | R | 40 | 13 | 13 | 3 | 4 | 4.40 | .303 | 1.30 | 8.4 | 3.5 | 10.2 | 73.2 | 68 | 36 | 36 | 10 | 28 | 83 | 0 | 0 | 0 | 0 | 7 | 0 | 1 | 3.66 |
| CL | Dotel, O.Dotel, Octavio >> | 39 | 2012 | R | 60 | 32 | 0 | 2 | 1 | 1.93 | .285 | 1.19 | 7.9 | 3.1 | 12.1 | 32.2 | 28 | 7 | 7 | 4 | 11 | 43 | 0 | 17 | 2 | 0 | 0 | 0 | 0 | 2.97 |
| SU | Benoit, J.Benoit, Joaquin >> | 35 | 2012 | R | 57 | 34 | 0 | 0 | 1 | 2.67 | .279 | 1.13 | 7.4 | 3.0 | 11.7 | 33.2 | 27 | 10 | 10 | 4 | 11 | 43 | 0 | 3 | 2 | 0 | 0 | 1 | 0 | 3.06 |
| RP | Villarreal, B.Villarreal, Brayan >> | 25 | 2012 | R | 59 | 43 | 0 | 5 | 2 | 2.36 | .269 | 1.11 | 5.6 | 4.4 | 9.5 | 53.1 | 33 | 14 | 14 | 3 | 26 | 56 | 0 | 1 | 1 | 0 | 0 | 0 | 5 | 3.09 |
| RP | Valverde, J.Valverde, Jose >> | 33 | 2012 | R | 31 | 29 | 0 | 4 | 1 | 4.56 | .364 | 1.68 | 9.4 | 6.1 | 8.3 | 25.2 | 26 | 13 | 13 | 4 | 17 | 23 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 5.40 |