| SP | Weaver, J.Weaver, Jered >> | 30 | 2012 | R | 94 | 17 | 17 | 6 | 4 | 2.29 | .268 | 1.09 | 7.5 | 2.3 | 7.5 | 117.2 | 98 | 34 | 30 | 9 | 30 | 98 | 3 | 0 | 0 | 1 | 14 | 1 | 1 | 3.12 |
| SP | Hamels, C.Hamels, Cole >> | 24 | 2007 | L | 88 | 16 | 16 | 13 | 2 | 3.11 | .282 | 1.16 | 7.3 | 3.2 | 7.8 | 104.1 | 84 | 36 | 36 | 12 | 37 | 90 | 3 | 0 | 0 | 1 | 12 | 2 | 2 | 3.89 |
| SP | Greinke, Z.Greinke, Zack # >> | 29 | 2012 | R | 60 | 16 | 16 | 5 | 8 | 5.14 | .316 | 1.36 | 9.9 | 2.4 | 7.0 | 91.0 | 100 | 56 | 52 | 11 | 24 | 71 | 1 | 0 | 0 | 1 | 7 | 2 | 3 | 3.87 |
| SP | Santana, E.Santana, Ervin >> | 29 | 2012 | R | 43 | 13 | 13 | 4 | 3 | 5.05 | .324 | 1.39 | 8.8 | 3.6 | 6.6 | 57.0 | 56 | 32 | 32 | 7 | 23 | 42 | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 4.49 |
| SP | Williams, J.Williams, Jerome >> | 31 | 2012 | R | 22 | 14 | 13 | 1 | 1 | 2.77 | .298 | 1.23 | 7.7 | 3.6 | 7.1 | 48.2 | 41 | 16 | 15 | 9 | 19 | 38 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5.17 |
| CL | Frieri, E.Frieri, Ernesto >> | 26 | 2012 | R | 92 | 40 | 0 | 0 | 3 | 4.64 | .323 | 1.43 | 8.8 | 4.3 | 9.4 | 42.2 | 41 | 22 | 22 | 7 | 20 | 44 | 0 | 19 | 2 | 0 | 0 | 0 | 1 | 4.50 |
| RP | Marshall, S.Marshall, Sean >> | 30 | 2012 | L | 44 | 56 | 0 | 7 | 0 | 1.86 | .269 | 1.07 | 6.2 | 3.4 | 9.9 | 29.0 | 20 | 7 | 6 | 1 | 11 | 32 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2.48 |
| RP | Jepsen, K.Jepsen, Kevin >> | 28 | 2012 | R | 41 | 41 | 0 | 5 | 2 | 4.47 | .279 | 1.12 | 7.3 | 2.8 | 6.6 | 48.1 | 39 | 24 | 24 | 4 | 15 | 35 | 0 | 0 | 2 | 0 | 0 | 2 | 3 | 3.69 |
| RP | Takahashi, H.Takahashi, Hisanori >> | 37 | 2012 | L | 40 | 33 | 0 | 3 | 3 | 3.33 | .258 | 1.02 | 6.8 | 2.3 | 6.8 | 46.0 | 35 | 17 | 17 | 7 | 12 | 35 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.30 |