| SP | Harden, R.Harden, Rich >> | 25 | 2005 | R | 94 | 39 | 39 | 22 | 8 | 3.20 | .282 | 1.16 | 6.5 | 3.9 | 7.3 | 256.1 | 186 | 92 | 91 | 21 | 111 | 207 | 2 | 0 | 0 | 0 | 28 | 5 | 14 | 3.81 |
| SP | Mulder, M.Mulder, Mark >> | 29 | 2002 | L | 84 | 36 | 36 | 19 | 11 | 4.28 | .292 | 1.22 | 8.7 | 2.3 | 6.2 | 248.1 | 240 | 120 | 118 | 45 | 64 | 171 | 7 | 0 | 0 | 1 | 18 | 4 | 5 | 4.80 |
| SP | Blanton, J.Blanton, Joe >> | 26 | 2005 | R | 65 | 32 | 32 | 7 | 13 | 4.17 | .310 | 1.32 | 9.0 | 2.9 | 6.2 | 209.1 | 210 | 106 | 97 | 36 | 67 | 144 | 3 | 0 | 0 | 1 | 14 | 5 | 3 | 4.89 |
| CL | Street, H.Street, Huston >> | 23 | 2005 | R | 98 | 72 | 0 | 0 | 2 | 2.53 | .254 | 1.00 | 5.6 | 3.5 | 6.3 | 67.2 | 42 | 21 | 19 | 7 | 26 | 47 | 0 | 62 | 7 | 0 | 0 | 1 | 1 | 4.16 |
| SU | Duchscherer, J.Duchscherer, Justin >> | 29 | 2005 | R | 88 | 66 | 0 | 2 | 4 | 2.28 | .261 | 1.06 | 5.8 | 3.8 | 9.8 | 67.0 | 43 | 17 | 17 | 8 | 28 | 73 | 0 | 2 | 4 | 0 | 0 | 0 | 3 | 3.63 |
| RP | Isringhausen, J.Isringhausen, Jason # >> | 34 | 2004 | R | 71 | 66 | 0 | 8 | 6 | 4.17 | .288 | 1.21 | 8.3 | 2.7 | 7.4 | 73.1 | 67 | 38 | 34 | 14 | 22 | 60 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Bradford, C.Bradford, Chad >> | 31 | 2001 | R | 70 | 24 | 0 | 2 | 1 | 6.93 | .295 | 1.26 | 10.9 | 0.8 | 5.3 | 24.2 | 29 | 19 | 19 | 5 | 2 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.79 |
| RP | Vizcaino, L.Vizcaino, Luis >> | 32 | 2002 | R | 70 | 23 | 0 | 2 | 0 | 4.37 | .306 | 1.28 | 8.6 | 3.3 | 7.8 | 22.2 | 21 | 11 | 11 | 1 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 3.09 |
| SP | Harang, A.Harang, Aaron >> | 28 | 2003 | R | 51 | 13 | 1 | 6 | 2 | 5.08 | .294 | 1.21 | 8.3 | 2.6 | 6.0 | 51.1 | 47 | 30 | 29 | 11 | 15 | 34 | 0 | 0 | 0 | 0 | 1 | 2 | 2 | 5.47 |