| SP | Jurrjens, J.Jurrjens, Jair >> | 24 | 2007 | R | 97 | 7 | 7 | 1 | 3 | 5.55 | .335 | 1.46 | 8.7 | 4.6 | 5.9 | 35.2 | 34 | 22 | 22 | 6 | 18 | 23 | 0 | 0 | 0 | 0 | 1 | 2 | 0 | 5.63 |
| SP | Bonderman, J.Bonderman, Jeremy >> | 28 | 2004 | R | 91 | 7 | 7 | 5 | 1 | 1.59 | .220 | 0.83 | 5.0 | 2.6 | 7.6 | 56.2 | 31 | 10 | 10 | 2 | 16 | 47 | 1 | 0 | 0 | 0 | 6 | 1 | 2 | 2.70 |
| SP | Galarraga, A.Galarraga, Armando >> | 28 | 2008 | R | 83 | 6 | 6 | 4 | 1 | 2.66 | .241 | 0.93 | 6.8 | 1.6 | 5.7 | 44.0 | 33 | 18 | 13 | 6 | 8 | 28 | 1 | 0 | 0 | 1 | 4 | 1 | 1 | 4.11 |
| SP | Verlander, J.Verlander, Justin # >> | 27 | 2007 | R | 85 | 7 | 7 | 2 | 5 | 5.57 | .326 | 1.43 | 9.0 | 3.9 | 8.6 | 42.0 | 42 | 31 | 26 | 6 | 18 | 40 | 0 | 0 | 0 | 0 | 3 | 1 | 2 | 4.31 |
| SP | Van Hekken, A.Van Hekken, Andy >> | 31 | 2002 | L | 84 | 6 | 6 | 2 | 2 | 4.43 | .304 | 1.31 | 9.9 | 2.1 | 6.2 | 42.2 | 46 | 24 | 21 | 4 | 10 | 29 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 3.57 |
| RP | Zumaya, J.Zumaya, Joel >> | 26 | 2006 | R | 99 | 18 | 0 | 2 | 0 | 2.94 | .299 | 1.22 | 8.5 | 2.7 | 9.0 | 33.2 | 31 | 12 | 11 | 2 | 10 | 33 | 0 | 3 | 2 | 0 | 0 | 2 | 1 | 2.88 |
| RP | Farnsworth, K.Farnsworth, Kyle >> | 34 | 2005 | R | 87 | 10 | 0 | 0 | 0 | 0.00 | .211 | 0.80 | 4.5 | 2.7 | 8.1 | 10.0 | 5 | 0 | 0 | 0 | 3 | 9 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 2.10 |
| RP | Valverde, J.Valverde, Jose >> | 31 | 2010 | R | 87 | 6 | 0 | 1 | 1 | 6.23 | .235 | 0.92 | 4.5 | 4.5 | 13.5 | 4.1 | 2 | 3 | 3 | 1 | 2 | 6 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 4.75 |
| RP | Anderson, M.Anderson, Matt >> | 34 | 1998 | R | 82 | 2 | 0 | 0 | 0 | 5.40 | .444 | 2.40 | 18.0 | 18.0 | 0.0 | 1.2 | 2 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.00 |