| SP | Severino, L.Severino, Luis † >> | 28 | 2022 | R | 97 | 36 | 36 | 17 | 11 | 2.66 | .251 | 0.99 | 6.3 | 2.7 | 8.6 | 216.2 | 150 | 68 | 64 | 18 | 65 | 207 | 0 | 0 | 0 | 0 | 23 | 3 | 4 | 3.11 |
| SP | Cortes Jr., N.Cortes Jr., Nestor † >> | 27 | 2022 | L | 100 | 37 | 37 | 14 | 10 | 2.99 | .264 | 1.06 | 7.1 | 2.4 | 8.7 | 223.0 | 177 | 76 | 74 | 22 | 60 | 215 | 0 | 0 | 0 | 0 | 23 | 3 | 0 | 3.20 |
| SP | Russo, M.Russo, Marius >> | 25 | 1939 | L | 81 | 35 | 35 | 18 | 6 | 3.12 | .271 | 1.10 | 7.1 | 2.8 | 4.5 | 204.2 | 161 | 81 | 71 | 20 | 64 | 103 | 2 | 0 | 0 | 2 | 19 | 3 | 2 | 4.25 |
| RP | German, D.German, Domingo >> | 29 | 2022 | R | 50 | 27 | 0 | 0 | 0 | 1.52 | .245 | 0.93 | 6.7 | 2.0 | 8.2 | 23.2 | 17 | 5 | 4 | 2 | 5 | 21 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.09 |
| RP | Peralta, W.Peralta, Wandy >> | 30 | 2022 | L | 74 | 100 | 0 | 2 | 1 | 3.28 | .312 | 1.34 | 9.4 | 2.8 | 5.9 | 49.1 | 51 | 20 | 18 | 3 | 15 | 32 | 0 | 0 | 2 | 0 | 0 | 1 | 3 | 3.47 |
| RP | Montgomery, J.Montgomery, Jordan >> | 29 | 2022 | L | 59 | 62 | 8 | 1 | 5 | 4.42 | .314 | 1.36 | 8.5 | 3.7 | 3.8 | 59.0 | 56 | 37 | 29 | 6 | 24 | 25 | 0 | 1 | 1 | 0 | 3 | 1 | 1 | 4.75 |
| RP | Marinaccio, R.Marinaccio, Ron >> | 26 | 2022 | R | 91 | 27 | 0 | 1 | 2 | 4.68 | .336 | 1.52 | 7.6 | 6.1 | 8.3 | 25.0 | 21 | 14 | 13 | 3 | 17 | 23 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.76 |
| RP | Hildebrand, O.Hildebrand, Oral >> | 32 | 1939 | R | 57 | 37 | 0 | 2 | 2 | 4.23 | .346 | 1.59 | 10.0 | 4.7 | 7.0 | 27.2 | 30 | 18 | 13 | 5 | 14 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 5.41 |
| RP | Effross, S.Effross, Scott >> | 28 | 2022 | R | 73 | 44 | 0 | 1 | 1 | 4.73 | .388 | 1.88 | 11.7 | 5.2 | 8.1 | 40.0 | 52 | 24 | 21 | 3 | 23 | 36 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 3.98 |
| SP | Ruffing, R.Ruffing, Red >> | 34 | 1939 | R | 48 | 25 | 24 | 10 | 5 | 4.88 | .315 | 1.37 | 8.8 | 3.7 | 4.3 | 147.2 | 143 | 90 | 80 | 7 | 60 | 70 | 4 | 0 | 0 | 2 | 11 | 1 | 3 | 3.91 |
| RP | Schmidt, C.Schmidt, Clarke >> | 26 | 2022 | R | 55 | 4 | 0 | 0 | 0 | 6.00 | .438 | 2.33 | 12.0 | 9.0 | 9.0 | 3.0 | 4 | 7 | 2 | 2 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 12.67 |
| SP | Taillon, J.Taillon, Jameson >> | 30 | 2022 | R | 65 | 5 | 0 | 0 | 2 | 9.24 | .406 | 2.05 | 12.8 | 6.8 | 7.5 | 12.2 | 17 | 13 | 13 | 3 | 9 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.83 |
| SU | Holmes, C.Holmes, Clay >> | 29 | 2022 | R | 85 | 58 | 0 | 3 | 8 | 4.12 | .296 | 1.24 | 8.3 | 3.0 | 6.7 | 54.2 | 50 | 26 | 25 | 5 | 18 | 40 | 0 | 29 | 8 | 0 | 0 | 1 | 1 | 3.78 |