| SP | Santana, J.Santana, Johan >> | 27 | 2006 | L | 93 | 35 | 35 | 14 | 14 | 4.38 | .306 | 1.31 | 9.1 | 2.7 | 8.1 | 205.1 | 207 | 106 | 100 | 19 | 61 | 185 | 2 | 0 | 0 | 1 | 16 | 3 | 2 | 3.34 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 96 | 34 | 34 | 15 | 11 | 4.22 | .288 | 1.20 | 8.2 | 2.6 | 8.1 | 179.0 | 163 | 86 | 84 | 25 | 51 | 162 | 0 | 0 | 0 | 0 | 13 | 3 | 9 | 3.91 |
| SP | Pineda, M.Pineda, Michael >> | 30 | 2019 | R | 63 | 35 | 24 | 5 | 12 | 5.03 | .322 | 1.41 | 9.7 | 3.0 | 6.2 | 157.1 | 169 | 90 | 88 | 17 | 53 | 109 | 0 | 0 | 0 | 0 | 10 | 2 | 4 | 4.07 |
| RP | Rogers, T.Rogers, Taylor >> | 28 | 2019 | L | 80 | 114 | 0 | 2 | 3 | 3.83 | .302 | 1.28 | 9.2 | 2.3 | 6.7 | 54.0 | 55 | 25 | 23 | 10 | 14 | 40 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.76 |
| RP | Duffey, T.Duffey, Tyler >> | 28 | 2019 | R | 86 | 83 | 0 | 3 | 4 | 4.25 | .306 | 1.29 | 9.1 | 2.6 | 8.4 | 65.2 | 66 | 32 | 31 | 4 | 19 | 61 | 0 | 0 | 3 | 0 | 0 | 2 | 4 | 2.89 |
| RP | Reyes, D.Reyes, Dennys >> | 29 | 2006 | L | 87 | 87 | 0 | 0 | 1 | 4.14 | .303 | 1.31 | 8.1 | 3.7 | 5.5 | 41.1 | 37 | 19 | 19 | 2 | 17 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.66 |
| SP | Berrios, J.Berrios, Jose >> | 25 | 2019 | R | 51 | 2 | 1 | 0 | 1 | 3.52 | .361 | 1.70 | 11.6 | 5.1 | 7.7 | 7.2 | 9 | 3 | 3 | 1 | 4 | 6 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.86 |
| CL | Nathan, J.Nathan, Joe † >> | 32 | 2006 | R | 99 | 64 | 0 | 4 | 5 | 2.39 | .256 | 1.00 | 5.8 | 3.4 | 7.3 | 67.2 | 43 | 18 | 18 | 4 | 25 | 54 | 0 | 44 | 3 | 0 | 0 | 2 | 4 | 3.37 |
| SP | Odorizzi, J.Odorizzi, Jake >> | 29 | 2019 | R | 67 | 17 | 8 | 1 | 4 | 7.94 | .414 | 2.12 | 13.1 | 6.0 | 8.1 | 51.0 | 74 | 45 | 45 | 8 | 34 | 46 | 0 | 0 | 0 | 0 | 1 | 0 | 2 | 5.24 |
| SU | Williams, S.Williams, Stan >> | 34 | 1970 | R | 73 | 53 | 0 | 2 | 2 | 2.50 | .278 | 1.15 | 6.8 | 3.6 | 5.2 | 50.1 | 38 | 16 | 14 | 4 | 20 | 29 | 0 | 6 | 5 | 0 | 0 | 0 | 0 | 4.08 |
| SP | Blyleven, B.Blyleven, Bert >> | 19 | 1970 | R | 68 | 29 | 24 | 5 | 12 | 4.96 | .327 | 1.44 | 9.4 | 3.5 | 5.9 | 147.0 | 154 | 89 | 81 | 18 | 57 | 96 | 1 | 0 | 0 | 0 | 12 | 3 | 0 | 4.51 |