| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 88 | 0 | 7 | 8 | 5.49 | .314 | 1.36 | 9.3 | 2.9 | 7.3 | 105.0 | 109 | 69 | 64 | 15 | 34 | 85 | 0 | 9 | 9 | 0 | 0 | 1 | 0 | 4.24 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 33 | 33 | 11 | 18 | 4.74 | .323 | 1.41 | 9.9 | 2.9 | 4.3 | 239.1 | 262 | 176 | 126 | 34 | 76 | 114 | 12 | 0 | 0 | 1 | 16 | 4 | 7 | 4.90 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 32 | 32 | 10 | 17 | 5.78 | .345 | 1.55 | 10.5 | 3.5 | 4.1 | 210.1 | 246 | 159 | 135 | 30 | 81 | 95 | 5 | 0 | 0 | 1 | 13 | 6 | 3 | 5.20 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 32 | 32 | 10 | 16 | 3.61 | .292 | 1.22 | 8.3 | 2.7 | 7.8 | 254.0 | 234 | 122 | 102 | 28 | 75 | 221 | 9 | 0 | 0 | 1 | 19 | 6 | 5 | 3.65 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 32 | 32 | 11 | 10 | 4.06 | .316 | 1.37 | 8.8 | 3.5 | 4.7 | 206.0 | 202 | 119 | 93 | 22 | 81 | 107 | 0 | 0 | 0 | 0 | 17 | 3 | 2 | 4.57 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 51 | 0 | 1 | 3 | 4.47 | .356 | 1.55 | 8.6 | 5.4 | 8.3 | 48.1 | 46 | 30 | 24 | 4 | 29 | 44 | 0 | 6 | 0 | 0 | 0 | 5 | 2 | 4.38 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 41 | 0 | 1 | 0 | 3.25 | .281 | 1.16 | 7.4 | 3.1 | 9.2 | 55.1 | 45 | 21 | 20 | 4 | 19 | 56 | 0 | 4 | 1 | 0 | 0 | 1 | 1 | 3.00 |