| SP | Buehrle, M.Buehrle, Mark >> | 27 | 2001 | L | 90 | 33 | 33 | 10 | 19 | 3.35 | .262 | 1.03 | 7.7 | 1.5 | 6.1 | 269.0 | 231 | 105 | 100 | 28 | 46 | 182 | 18 | 0 | 0 | 6 | 19 | 10 | 2 | 3.62 |
| SP | McCarthy, B.McCarthy, Brandon # >> | 23 | 2005 | R | 70 | 32 | 32 | 5 | 12 | 4.86 | .332 | 1.44 | 10.3 | 2.8 | 6.8 | 129.2 | 147 | 76 | 70 | 21 | 40 | 98 | 0 | 0 | 0 | 0 | 6 | 6 | 0 | 4.67 |
| SP | Garland, J.Garland, Jon >> | 27 | 2005 | R | 64 | 32 | 32 | 8 | 12 | 4.38 | .317 | 1.37 | 9.5 | 2.8 | 6.2 | 156.0 | 164 | 81 | 76 | 22 | 49 | 107 | 1 | 0 | 0 | 0 | 14 | 4 | 3 | 4.48 |
| RP | Barcelo, L.Barcelo, Lorenzo >> | 29 | 2000 | R | 97 | 78 | 0 | 6 | 7 | 3.24 | .270 | 1.09 | 7.5 | 2.3 | 6.7 | 158.1 | 132 | 57 | 57 | 17 | 40 | 118 | 0 | 3 | 2 | 0 | 0 | 4 | 1 | 3.74 |
| RP | Ginter, M.Ginter, Matt >> | 29 | 2001 | R | 95 | 79 | 0 | 13 | 1 | 3.06 | .267 | 1.05 | 6.4 | 3.1 | 7.2 | 123.2 | 87 | 45 | 42 | 7 | 43 | 99 | 0 | 4 | 5 | 0 | 0 | 5 | 4 | 3.30 |
| RP | Marte, D.Marte, Damaso >> | 31 | 2002 | L | 93 | 102 | 0 | 2 | 2 | 3.62 | .308 | 1.34 | 8.4 | 3.6 | 8.9 | 77.0 | 72 | 34 | 31 | 12 | 31 | 76 | 0 | 5 | 2 | 0 | 0 | 0 | 3 | 4.26 |
| RP | Foulke, K.Foulke, Keith >> | 34 | 2003 | R | 84 | 76 | 0 | 5 | 2 | 2.15 | .247 | 0.93 | 5.8 | 2.6 | 7.7 | 67.0 | 43 | 18 | 16 | 3 | 19 | 57 | 0 | 5 | 3 | 0 | 0 | 4 | 0 | 2.91 |