| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 99 | 18 | 18 | 3 | 9 | 5.01 | .337 | 1.48 | 10.3 | 3.1 | 8.7 | 116.2 | 133 | 67 | 65 | 16 | 40 | 112 | 1 | 0 | 0 | 1 | 8 | 5 | 2 | 4.03 |
| SP | Carpenter, C.Carpenter, Chris >> | 34 | 2009 | R | 81 | 17 | 17 | 2 | 8 | 6.20 | .359 | 1.61 | 11.4 | 3.2 | 7.2 | 101.2 | 128 | 75 | 70 | 14 | 36 | 81 | 1 | 0 | 0 | 0 | 6 | 7 | 1 | 4.48 |
| SP | Hamels, C.Hamels, Cole >> | 25 | 2008 | L | 73 | 17 | 17 | 6 | 7 | 5.32 | .316 | 1.35 | 9.3 | 3.0 | 7.0 | 106.2 | 109 | 65 | 63 | 28 | 35 | 83 | 1 | 0 | 0 | 1 | 7 | 4 | 0 | 5.97 |
| SP | Mussina, M.Mussina, Mike >> | 33 | 2001 | R | 69 | 17 | 17 | 5 | 6 | 4.45 | .323 | 1.39 | 10.3 | 2.2 | 5.9 | 115.1 | 132 | 69 | 57 | 18 | 28 | 75 | 1 | 0 | 0 | 1 | 9 | 5 | 4 | 4.59 |
| SP | Santana, E.Santana, Ervin >> | 25 | 2008 | R | 56 | 17 | 17 | 2 | 5 | 5.33 | .340 | 1.53 | 10.9 | 2.9 | 6.8 | 104.2 | 126 | 65 | 62 | 20 | 34 | 78 | 0 | 0 | 0 | 0 | 7 | 2 | 3 | 5.04 |
| RP | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 100 | 55 | 0 | 9 | 2 | 2.59 | .290 | 1.23 | 7.8 | 3.3 | 9.9 | 80.0 | 69 | 26 | 23 | 8 | 29 | 88 | 0 | 3 | 1 | 0 | 0 | 0 | 2 | 3.19 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 89 | 48 | 0 | 4 | 4 | 7.79 | .416 | 2.10 | 13.0 | 5.9 | 10.6 | 52.0 | 75 | 53 | 45 | 7 | 34 | 61 | 0 | 3 | 2 | 0 | 0 | 2 | 1 | 4.48 |
| RP | Springer, R.Springer, Russ † >> | 39 | 2007 | R | 79 | 42 | 0 | 6 | 1 | 5.48 | .356 | 1.66 | 9.2 | 5.9 | 10.3 | 47.2 | 48 | 29 | 29 | 3 | 31 | 54 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 3.51 |
| RP | Takatsu, S.Takatsu, Shingo >> | 36 | 2004 | R | 57 | 23 | 0 | 2 | 1 | 4.88 | .336 | 1.48 | 10.0 | 3.7 | 6.0 | 27.2 | 30 | 15 | 15 | 5 | 11 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 5.41 |