| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 33 | 33 | 11 | 16 | 4.51 | .312 | 1.32 | 9.4 | 2.5 | 7.5 | 211.1 | 220 | 126 | 106 | 32 | 58 | 175 | 5 | 0 | 0 | 1 | 16 | 9 | 5 | 4.27 |
| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 33 | 33 | 14 | 9 | 4.83 | .306 | 1.30 | 8.9 | 2.8 | 8.3 | 188.1 | 185 | 104 | 101 | 25 | 59 | 174 | 2 | 0 | 0 | 0 | 13 | 5 | 2 | 3.90 |
| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 97 | 33 | 32 | 13 | 9 | 5.31 | .323 | 1.40 | 9.2 | 3.4 | 8.9 | 189.2 | 194 | 116 | 112 | 31 | 72 | 187 | 7 | 0 | 0 | 1 | 13 | 6 | 2 | 4.39 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 81 | 0 | 3 | 5 | 5.25 | .330 | 1.47 | 9.8 | 3.4 | 8.2 | 106.1 | 116 | 64 | 62 | 15 | 40 | 97 | 0 | 4 | 8 | 0 | 0 | 1 | 1 | 4.17 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 98 | 84 | 0 | 6 | 0 | 1.81 | .257 | 1.01 | 6.1 | 3.0 | 8.5 | 99.1 | 67 | 20 | 20 | 7 | 33 | 93 | 0 | 10 | 1 | 0 | 0 | 3 | 0 | 3.13 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 61 | 0 | 1 | 3 | 4.03 | .271 | 1.11 | 8.0 | 2.1 | 8.8 | 73.2 | 65 | 35 | 33 | 8 | 17 | 71 | 0 | 7 | 5 | 0 | 0 | 0 | 1 | 3.18 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 93 | 60 | 0 | 4 | 4 | 4.30 | .345 | 1.57 | 9.6 | 4.6 | 8.4 | 75.1 | 80 | 47 | 36 | 14 | 38 | 70 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 5.12 |