| SP | deGrom, J.deGrom, Jacob # >> | 33 | 2021 | R | 100 | 33 | 33 | 18 | 7 | 3.51 | .237 | 0.91 | 6.8 | 1.4 | 10.1 | 212.2 | 159 | 88 | 83 | 32 | 34 | 238 | 2 | 0 | 0 | 1 | 24 | 5 | 0 | 3.27 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 92 | 32 | 32 | 11 | 10 | 5.40 | .318 | 1.37 | 9.5 | 2.8 | 4.7 | 170.0 | 180 | 109 | 102 | 33 | 53 | 89 | 5 | 0 | 0 | 1 | 11 | 5 | 4 | 5.50 |
| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 32 | 32 | 18 | 4 | 3.71 | .283 | 1.17 | 7.7 | 2.9 | 5.6 | 225.2 | 192 | 95 | 93 | 24 | 73 | 140 | 9 | 0 | 0 | 4 | 18 | 2 | 1 | 4.14 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 71 | 33 | 32 | 13 | 9 | 4.19 | .297 | 1.27 | 8.1 | 3.4 | 5.5 | 200.0 | 179 | 101 | 93 | 26 | 75 | 122 | 1 | 0 | 0 | 0 | 19 | 0 | 6 | 4.60 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 78 | 0 | 7 | 2 | 2.28 | .207 | 0.76 | 4.8 | 2.1 | 8.1 | 87.0 | 46 | 24 | 22 | 8 | 20 | 78 | 0 | 34 | 4 | 0 | 0 | 2 | 2 | 3.16 |
| SU | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 75 | 0 | 2 | 1 | 2.12 | .271 | 1.12 | 5.5 | 4.6 | 9.8 | 85.0 | 52 | 20 | 20 | 6 | 43 | 93 | 0 | 6 | 2 | 0 | 0 | 0 | 2 | 3.25 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 89 | 85 | 0 | 14 | 3 | 2.86 | .257 | 1.03 | 5.5 | 3.7 | 10.4 | 104.0 | 64 | 35 | 33 | 14 | 43 | 120 | 0 | 0 | 1 | 0 | 0 | 1 | 3 | 3.71 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 75 | 65 | 0 | 8 | 5 | 3.28 | .284 | 1.18 | 7.1 | 3.5 | 8.8 | 82.1 | 65 | 31 | 30 | 7 | 32 | 80 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 3.37 |