| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 10 | 10 | 4 | 4 | 3.36 | .269 | 1.11 | 7.2 | 2.8 | 5.3 | 75.0 | 60 | 33 | 28 | 6 | 23 | 44 | 4 | 0 | 0 | 1 | 6 | 0 | 1 | 3.79 |
| SP | Mathewson, C.Mathewson, Christy # >> | 28 | 1908 | R | 82 | 10 | 10 | 3 | 4 | 5.19 | .331 | 1.47 | 11.3 | 2.1 | 5.1 | 60.2 | 75 | 39 | 35 | 7 | 14 | 34 | 1 | 0 | 0 | 0 | 5 | 1 | 0 | 4.13 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 10 | 10 | 5 | 5 | 3.81 | .282 | 1.18 | 8.4 | 2.3 | 4.1 | 75.2 | 70 | 32 | 32 | 13 | 19 | 34 | 3 | 0 | 0 | 1 | 6 | 0 | 0 | 5.11 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 10 | 10 | 2 | 7 | 6.63 | .364 | 1.72 | 12.3 | 3.2 | 4.3 | 57.0 | 78 | 43 | 42 | 5 | 20 | 27 | 1 | 0 | 0 | 1 | 2 | 0 | 2 | 4.25 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 8 | 8 | 4 | 1 | 4.45 | .314 | 1.34 | 8.3 | 3.8 | 6.7 | 54.2 | 50 | 28 | 27 | 4 | 23 | 40 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 3.87 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 22 | 0 | 1 | 0 | 2.51 | .232 | 0.84 | 4.5 | 3.2 | 7.7 | 28.2 | 14 | 9 | 8 | 3 | 10 | 24 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 3.96 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 22 | 0 | 2 | 0 | 3.10 | .250 | 1.00 | 7.1 | 1.9 | 8.1 | 29.0 | 23 | 10 | 10 | 5 | 6 | 26 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 4.07 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 66 | 19 | 0 | 0 | 2 | 7.79 | .409 | 2.08 | 15.4 | 3.7 | 9.0 | 17.1 | 29 | 15 | 15 | 4 | 7 | 17 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 5.29 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 57 | 16 | 0 | 1 | 3 | 4.01 | .327 | 1.46 | 6.4 | 7.1 | 5.6 | 24.2 | 17 | 12 | 11 | 3 | 19 | 15 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 5.75 |
| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 57 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 6 | 0 | 0 | 0 | 8.22 | .343 | 1.57 | 10.3 | 5.1 | 6.4 | 7.2 | 8 | 8 | 7 | 4 | 4 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 10.71 |