| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 13 | 13 | 4 | 8 | 5.15 | .306 | 1.32 | 8.8 | 3.2 | 9.1 | 99.2 | 97 | 61 | 57 | 10 | 35 | 100 | 4 | 0 | 0 | 0 | 7 | 0 | 1 | 3.35 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 13 | 13 | 3 | 8 | 5.34 | .313 | 1.36 | 9.7 | 2.6 | 8.9 | 96.0 | 103 | 58 | 57 | 11 | 28 | 95 | 1 | 0 | 0 | 0 | 5 | 0 | 3 | 3.39 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 13 | 13 | 5 | 7 | 4.93 | .308 | 1.32 | 8.9 | 2.9 | 7.5 | 95.0 | 94 | 53 | 52 | 13 | 31 | 79 | 1 | 0 | 0 | 0 | 4 | 2 | 2 | 4.16 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 13 | 13 | 4 | 6 | 4.11 | .309 | 1.29 | 7.9 | 3.8 | 5.2 | 103.0 | 90 | 49 | 47 | 6 | 43 | 59 | 6 | 0 | 0 | 1 | 7 | 5 | 4 | 4.01 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 13 | 5 | 5 | 5.98 | .364 | 1.71 | 10.6 | 4.9 | 4.3 | 87.1 | 102 | 60 | 58 | 10 | 47 | 42 | 0 | 0 | 0 | 0 | 5 | 1 | 2 | 5.18 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 28 | 0 | 2 | 1 | 2.65 | .311 | 1.32 | 6.4 | 5.6 | 8.2 | 34.0 | 24 | 10 | 10 | 3 | 21 | 31 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.26 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 22 | 0 | 2 | 1 | 2.25 | .209 | 0.75 | 3.8 | 3.0 | 7.1 | 24.0 | 10 | 6 | 6 | 1 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.08 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 8 | 0 | 0 | 0 | 0.00 | .296 | 1.18 | 7.5 | 3.8 | 9.8 | 12.2 | 10 | 0 | 0 | 0 | 5 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.33 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 15 | 0 | 1 | 0 | 1.76 | .233 | 0.91 | 4.8 | 3.6 | 5.4 | 15.1 | 8 | 3 | 3 | 1 | 6 | 9 | 0 | 10 | 1 | 0 | 0 | 0 | 0 | 3.87 |