| SP | Koufax, S.Koufax, Sandy # >> | 30 | 1965 | L | 97 | 13 | 13 | 7 | 4 | 2.98 | .258 | 1.02 | 6.3 | 3.0 | 8.1 | 102.2 | 71 | 35 | 34 | 11 | 34 | 92 | 6 | 0 | 0 | 1 | 9 | 2 | 3 | 3.66 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 13 | 13 | 8 | 4 | 4.17 | .318 | 1.37 | 9.1 | 3.2 | 4.5 | 95.0 | 96 | 45 | 44 | 9 | 34 | 47 | 3 | 0 | 0 | 1 | 8 | 3 | 3 | 4.41 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 13 | 13 | 3 | 7 | 7.64 | .397 | 1.95 | 11.6 | 5.9 | 7.5 | 73.0 | 94 | 66 | 62 | 13 | 48 | 61 | 1 | 0 | 0 | 0 | 4 | 2 | 2 | 5.70 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 13 | 13 | 5 | 5 | 6.34 | .345 | 1.54 | 11.4 | 2.5 | 7.2 | 82.1 | 104 | 58 | 58 | 15 | 23 | 66 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 4.72 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 34 | 0 | 1 | 1 | 3.04 | .268 | 1.08 | 8.0 | 1.7 | 7.3 | 47.1 | 42 | 16 | 16 | 4 | 9 | 38 | 0 | 4 | 0 | 0 | 0 | 1 | 0 | 3.13 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 75 | 28 | 0 | 1 | 0 | 3.69 | .312 | 1.33 | 8.4 | 3.8 | 8.7 | 31.2 | 29 | 14 | 13 | 2 | 13 | 30 | 0 | 3 | 0 | 0 | 0 | 1 | 2 | 3.26 |
| RP | O'Day, D.O'Day, Darren >> | 28 | 2010 | R | 50 | 16 | 0 | 2 | 1 | 3.79 | .260 | 1.05 | 5.2 | 4.3 | 5.7 | 19.0 | 11 | 8 | 8 | 0 | 9 | 12 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.16 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 4 | 0 | 0 | 1 | 4.91 | .290 | 1.23 | 6.4 | 5.1 | 9.0 | 7.1 | 5 | 4 | 4 | 0 | 4 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.71 |