| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 28 | 28 | 11 | 7 | 4.59 | .299 | 1.27 | 8.7 | 2.7 | 7.9 | 176.1 | 171 | 91 | 90 | 28 | 53 | 155 | 0 | 0 | 0 | 0 | 14 | 2 | 5 | 4.24 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 28 | 28 | 12 | 9 | 3.69 | .277 | 1.14 | 8.2 | 2.0 | 4.5 | 212.0 | 194 | 93 | 87 | 26 | 47 | 106 | 9 | 0 | 0 | 1 | 17 | 3 | 4 | 4.30 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 26 | 26 | 11 | 10 | 4.10 | .335 | 1.49 | 9.4 | 4.1 | 5.6 | 182.1 | 190 | 100 | 83 | 11 | 82 | 113 | 0 | 0 | 0 | 0 | 15 | 4 | 3 | 3.96 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 72 | 0 | 5 | 1 | 3.93 | .313 | 1.35 | 8.0 | 4.2 | 9.1 | 71.0 | 63 | 32 | 31 | 10 | 33 | 72 | 0 | 4 | 1 | 0 | 0 | 1 | 0 | 4.24 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 67 | 0 | 5 | 5 | 2.92 | .277 | 1.11 | 7.7 | 2.3 | 8.5 | 86.1 | 74 | 30 | 28 | 7 | 22 | 81 | 0 | 15 | 2 | 0 | 0 | 3 | 1 | 3.05 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 49 | 0 | 5 | 5 | 4.76 | .317 | 1.39 | 8.2 | 4.5 | 6.8 | 56.2 | 51 | 31 | 30 | 12 | 28 | 42 | 0 | 6 | 3 | 0 | 0 | 0 | 1 | 5.79 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 2 | 2 | 1 | 0 | 3.60 | .297 | 1.27 | 7.8 | 3.6 | 8.4 | 15.0 | 13 | 7 | 6 | 0 | 6 | 14 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.33 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 1 | 0 | 0 | 1 | 4.50 | .143 | 0.50 | 4.5 | 0.0 | 4.5 | 2.0 | 1 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.50 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 17 | 0 | 3 | 1 | 2.68 | .284 | 1.16 | 7.3 | 3.2 | 3.9 | 37.0 | 30 | 11 | 11 | 3 | 13 | 16 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.32 |