| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 16 | 16 | 5 | 6 | 3.50 | .302 | 1.28 | 6.6 | 5.1 | 5.6 | 92.2 | 67 | 36 | 36 | 7 | 52 | 57 | 1 | 0 | 0 | 1 | 6 | 1 | 1 | 4.48 |
| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 16 | 16 | 7 | 4 | 4.96 | .289 | 1.22 | 8.7 | 2.3 | 6.1 | 103.1 | 100 | 61 | 57 | 18 | 26 | 70 | 3 | 0 | 0 | 1 | 7 | 0 | 2 | 4.67 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 16 | 16 | 9 | 6 | 3.31 | .294 | 1.24 | 7.9 | 3.3 | 5.0 | 114.1 | 100 | 45 | 42 | 9 | 42 | 63 | 4 | 0 | 0 | 1 | 10 | 1 | 5 | 4.05 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 37 | 0 | 1 | 0 | 2.63 | .231 | 0.90 | 5.7 | 2.4 | 7.0 | 41.0 | 26 | 12 | 12 | 4 | 11 | 32 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3.51 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 45 | 0 | 0 | 0 | 2.76 | .273 | 1.13 | 7.4 | 2.8 | 8.7 | 29.1 | 24 | 9 | 9 | 5 | 9 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.24 |
| RP | Abernathy, T.Abernathy, Ted >> | 34 | 1967 | R | 49 | 30 | 0 | 4 | 2 | 2.13 | .255 | 1.03 | 5.2 | 4.0 | 4.0 | 38.0 | 22 | 14 | 9 | 2 | 17 | 17 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.13 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 28 | 0 | 4 | 2 | 4.45 | .316 | 1.35 | 8.7 | 3.6 | 9.3 | 30.1 | 29 | 15 | 15 | 6 | 12 | 31 | 0 | 10 | 2 | 0 | 0 | 1 | 1 | 4.83 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 4 | 0 | 1 | 0 | 10.80 | .444 | 2.40 | 12.0 | 12.0 | 15.0 | 3.1 | 4 | 4 | 4 | 1 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.00 |