| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 99 | 10 | 10 | 3 | 5 | 3.33 | .280 | 1.11 | 9.2 | 0.7 | 6.8 | 73.0 | 75 | 29 | 27 | 8 | 6 | 55 | 2 | 0 | 0 | 0 | 6 | 4 | 0 | 3.33 |
| SP | Richard, J.Richard, J.R. >> | 30 | 1980 | R | 90 | 10 | 10 | 5 | 3 | 2.56 | .298 | 1.27 | 6.6 | 5.0 | 7.6 | 59.2 | 43 | 23 | 17 | 4 | 33 | 50 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 3.86 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 10 | 10 | 3 | 7 | 5.17 | .338 | 1.53 | 10.6 | 3.3 | 7.8 | 62.2 | 73 | 41 | 36 | 10 | 23 | 54 | 2 | 0 | 0 | 1 | 5 | 0 | 1 | 4.47 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 10 | 10 | 3 | 6 | 5.14 | .307 | 1.31 | 9.6 | 2.2 | 4.9 | 70.0 | 75 | 42 | 40 | 9 | 17 | 38 | 2 | 0 | 0 | 0 | 5 | 1 | 1 | 4.36 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 10 | 10 | 3 | 3 | 3.98 | .293 | 1.23 | 8.6 | 2.5 | 4.8 | 72.1 | 69 | 34 | 32 | 13 | 20 | 38 | 1 | 0 | 0 | 1 | 5 | 1 | 0 | 5.17 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 22 | 0 | 1 | 2 | 7.27 | .371 | 1.73 | 10.4 | 5.2 | 10.4 | 26.0 | 30 | 21 | 21 | 2 | 15 | 30 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3.54 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 20 | 0 | 1 | 0 | 4.29 | .308 | 1.29 | 8.1 | 3.4 | 9.4 | 21.0 | 19 | 11 | 10 | 2 | 8 | 22 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 3.43 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 16 | 0 | 0 | 0 | 3.14 | .328 | 1.47 | 10.3 | 3.2 | 6.4 | 14.1 | 16 | 6 | 5 | 2 | 5 | 10 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 4.50 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 3 | 0 | 0 | 0 | 0.00 | .273 | 1.13 | 9.0 | 4.5 | 4.5 | 2.2 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.50 |