| SP | McNally, D.McNally, Dave † >> | 26 | 1968 | L | 96 | 29 | 29 | 18 | 7 | 3.96 | .307 | 1.32 | 9.2 | 2.6 | 5.5 | 211.1 | 216 | 99 | 93 | 27 | 62 | 128 | 4 | 0 | 0 | 0 | 18 | 3 | 3 | 4.37 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 29 | 29 | 7 | 12 | 5.23 | .310 | 1.34 | 10.2 | 2.0 | 7.9 | 180.2 | 203 | 111 | 105 | 35 | 39 | 158 | 4 | 0 | 0 | 0 | 13 | 2 | 4 | 4.46 |
| SP | Hunter, C.Hunter, Catfish † # >> | 26 | 1972 | R | 81 | 28 | 28 | 13 | 8 | 3.73 | .294 | 1.23 | 8.2 | 2.8 | 4.9 | 215.0 | 196 | 98 | 89 | 19 | 68 | 117 | 13 | 0 | 0 | 3 | 15 | 5 | 5 | 4.08 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 27 | 27 | 12 | 9 | 4.93 | .334 | 1.49 | 9.7 | 3.8 | 4.9 | 191.2 | 205 | 107 | 105 | 19 | 80 | 103 | 5 | 0 | 0 | 2 | 11 | 4 | 2 | 4.53 |
| RP | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 70 | 0 | 9 | 6 | 2.72 | .281 | 1.17 | 6.6 | 4.0 | 7.1 | 86.0 | 63 | 26 | 26 | 4 | 38 | 68 | 0 | 17 | 5 | 0 | 0 | 0 | 0 | 3.35 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 28 | 0 | 4 | 0 | 1.01 | .208 | 0.75 | 3.1 | 3.8 | 8.3 | 26.2 | 9 | 3 | 3 | 2 | 11 | 24 | 0 | 8 | 1 | 0 | 0 | 1 | 1 | 3.54 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 19 | 0 | 2 | 1 | 3.50 | .308 | 1.28 | 7.0 | 4.5 | 11.0 | 18.0 | 14 | 10 | 7 | 4 | 9 | 22 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 5.11 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 20 | 0 | 1 | 2 | 4.44 | .342 | 1.56 | 10.1 | 4.1 | 10.5 | 24.1 | 27 | 12 | 12 | 2 | 11 | 28 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.13 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 67 | 18 | 0 | 5 | 2 | 3.67 | .313 | 1.31 | 8.8 | 3.1 | 8.3 | 90.2 | 88 | 38 | 37 | 5 | 31 | 83 | 0 | 0 | 0 | 0 | 0 | 5 | 4 | 3.08 |