| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 7 | 7 | 2 | 4 | 3.12 | .278 | 1.08 | 7.1 | 2.6 | 8.7 | 52.0 | 41 | 21 | 18 | 3 | 15 | 50 | 0 | 0 | 0 | 0 | 6 | 4 | 0 | 2.92 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 7 | 7 | 5 | 1 | 4.15 | .255 | 0.99 | 6.9 | 2.1 | 5.0 | 47.2 | 36 | 22 | 22 | 2 | 11 | 26 | 1 | 0 | 0 | 0 | 4 | 2 | 0 | 3.28 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 7 | 7 | 2 | 4 | 6.15 | .310 | 1.32 | 9.0 | 3.0 | 8.8 | 45.1 | 45 | 32 | 31 | 5 | 15 | 44 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 3.56 |
| CL | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 17 | 0 | 0 | 2 | 3.21 | .276 | 1.14 | 7.7 | 2.6 | 7.1 | 14.0 | 12 | 5 | 5 | 0 | 4 | 11 | 0 | 13 | 1 | 0 | 0 | 0 | 0 | 2.29 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 18 | 0 | 1 | 0 | 1.93 | .282 | 1.18 | 5.0 | 6.0 | 13.0 | 9.1 | 5 | 2 | 2 | 0 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.11 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 4 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 13.5 | 4.0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0.00 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 11 | 0 | 0 | 0 | 3.00 | .357 | 1.67 | 7.5 | 7.5 | 10.5 | 6.0 | 5 | 2 | 2 | 0 | 5 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.17 |