| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 64 | 22 | 13 | 6 | 6 | 4.19 | .275 | 1.09 | 7.8 | 2.0 | 6.6 | 116.0 | 101 | 54 | 54 | 21 | 26 | 85 | 1 | 0 | 0 | 1 | 5 | 5 | 0 | 4.69 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 29 | 29 | 12 | 9 | 2.85 | .265 | 1.06 | 6.5 | 3.0 | 4.4 | 202.0 | 147 | 66 | 64 | 13 | 68 | 99 | 2 | 0 | 0 | 2 | 18 | 4 | 3 | 3.93 |
| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 28 | 28 | 16 | 7 | 3.16 | .253 | 1.00 | 7.4 | 1.6 | 7.1 | 211.0 | 174 | 78 | 74 | 21 | 37 | 167 | 8 | 0 | 0 | 2 | 19 | 3 | 3 | 3.28 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 81 | 28 | 28 | 12 | 11 | 3.71 | .278 | 1.15 | 7.7 | 2.6 | 5.3 | 199.0 | 170 | 85 | 82 | 10 | 58 | 118 | 4 | 0 | 0 | 1 | 17 | 2 | 1 | 3.37 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 46 | 0 | 2 | 2 | 1.86 | .190 | 0.70 | 4.1 | 2.3 | 9.6 | 48.1 | 22 | 10 | 10 | 6 | 12 | 51 | 0 | 33 | 4 | 0 | 0 | 0 | 0 | 3.25 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 92 | 71 | 0 | 2 | 1 | 3.42 | .282 | 1.18 | 6.1 | 4.5 | 11.5 | 50.0 | 34 | 19 | 19 | 3 | 25 | 64 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 2.72 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 54 | 0 | 1 | 5 | 2.36 | .277 | 1.15 | 7.5 | 2.9 | 7.5 | 49.2 | 41 | 17 | 13 | 4 | 16 | 41 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 3.37 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 36 | 0 | 2 | 5 | 3.62 | .326 | 1.45 | 9.3 | 3.9 | 8.4 | 32.1 | 33 | 13 | 13 | 4 | 14 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.06 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 21 | 17 | 5 | 8 | 4.17 | .305 | 1.30 | 8.7 | 3.1 | 4.7 | 131.2 | 126 | 63 | 61 | 16 | 45 | 69 | 5 | 0 | 0 | 2 | 9 | 2 | 2 | 4.61 |