| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 12 | 14 | 3.93 | .313 | 1.35 | 7.6 | 4.6 | 8.9 | 217.2 | 183 | 95 | 95 | 24 | 111 | 215 | 1 | 0 | 0 | 0 | 20 | 3 | 7 | 4.03 |
| SP | Cicotte, E.Cicotte, Eddie # >> | 33 | 1917 | R | 74 | 33 | 33 | 10 | 19 | 4.85 | .315 | 1.34 | 9.5 | 2.6 | 4.7 | 224.1 | 236 | 132 | 121 | 34 | 65 | 117 | 5 | 0 | 0 | 1 | 15 | 8 | 0 | 4.91 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 32 | 32 | 11 | 14 | 4.10 | .298 | 1.24 | 7.8 | 3.4 | 5.1 | 228.1 | 198 | 110 | 104 | 18 | 86 | 130 | 8 | 0 | 0 | 0 | 18 | 7 | 4 | 4.11 |
| SP | Caldwell, R.Caldwell, Ray # >> | 26 | 1914 | R | 63 | 32 | 32 | 7 | 16 | 5.52 | .344 | 1.56 | 10.5 | 3.6 | 4.2 | 187.1 | 219 | 121 | 115 | 25 | 74 | 88 | 0 | 0 | 0 | 0 | 11 | 2 | 3 | 5.02 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 89 | 0 | 8 | 3 | 3.17 | .279 | 1.13 | 7.9 | 2.3 | 9.0 | 130.2 | 114 | 47 | 46 | 14 | 33 | 130 | 0 | 12 | 6 | 0 | 0 | 5 | 4 | 3.28 |
| RP | Harvey, B.Harvey, Bryan >> | 28 | 1991 | R | 66 | 82 | 0 | 4 | 6 | 4.76 | .309 | 1.32 | 8.4 | 3.5 | 9.4 | 102.0 | 95 | 57 | 54 | 20 | 40 | 107 | 0 | 8 | 6 | 0 | 0 | 2 | 1 | 4.69 |
| RP | Russell, J.Russell, Jeff >> | 28 | 1989 | R | 57 | 61 | 0 | 2 | 4 | 4.37 | .325 | 1.41 | 7.3 | 5.5 | 8.2 | 59.2 | 48 | 31 | 29 | 6 | 36 | 54 | 0 | 9 | 3 | 0 | 0 | 2 | 5 | 4.42 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 57 | 4 | 1 | 0 | 2 | 4.63 | .314 | 1.37 | 7.4 | 5.7 | 5.7 | 11.2 | 9 | 6 | 6 | 3 | 7 | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.18 |
| SP | Schilling, C.Schilling, Curt >> | 36 | 2002 | R | 48 | 22 | 0 | 3 | 3 | 4.07 | .330 | 1.48 | 10.7 | 2.8 | 10.1 | 48.2 | 57 | 22 | 22 | 7 | 15 | 54 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.58 |