| SP | Johnson, W.Johnson, Walter † >> | 26 | 1913 | R | 95 | 29 | 29 | 18 | 3 | 3.77 | .263 | 1.05 | 7.4 | 2.1 | 4.7 | 210.0 | 173 | 91 | 88 | 25 | 48 | 110 | 3 | 0 | 0 | 1 | 16 | 4 | 2 | 4.24 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 29 | 29 | 14 | 11 | 4.32 | .336 | 1.49 | 9.1 | 4.3 | 8.0 | 200.0 | 203 | 105 | 96 | 21 | 95 | 178 | 2 | 0 | 0 | 0 | 14 | 6 | 1 | 4.10 |
| SP | Greinke, Z.Greinke, Zack # >> | 32 | 2015 | R | 94 | 28 | 28 | 8 | 11 | 4.92 | .299 | 1.26 | 8.6 | 2.8 | 6.4 | 190.1 | 181 | 108 | 104 | 27 | 59 | 135 | 4 | 0 | 0 | 1 | 12 | 4 | 3 | 4.42 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 27 | 27 | 10 | 9 | 3.94 | .294 | 1.23 | 9.2 | 1.8 | 4.7 | 196.1 | 201 | 101 | 86 | 24 | 40 | 103 | 3 | 0 | 0 | 1 | 14 | 4 | 0 | 4.21 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 66 | 0 | 4 | 8 | 3.58 | .277 | 1.12 | 7.3 | 2.8 | 8.9 | 70.1 | 57 | 30 | 28 | 5 | 22 | 69 | 0 | 38 | 6 | 0 | 0 | 2 | 1 | 2.99 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 81 | 56 | 0 | 4 | 4 | 4.82 | .326 | 1.45 | 8.2 | 5.0 | 8.9 | 65.1 | 59 | 38 | 35 | 8 | 36 | 64 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 4.29 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 41 | 0 | 3 | 1 | 2.33 | .249 | 0.95 | 5.1 | 3.5 | 9.2 | 46.1 | 26 | 13 | 12 | 6 | 18 | 47 | 0 | 4 | 2 | 0 | 0 | 2 | 0 | 3.96 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 38 | 0 | 2 | 1 | 4.08 | .312 | 1.34 | 8.5 | 3.7 | 5.1 | 39.2 | 37 | 20 | 18 | 4 | 16 | 22 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.51 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 11 | 0 | 1 | 1 | 2.03 | .333 | 1.50 | 9.7 | 4.2 | 1.4 | 13.1 | 14 | 3 | 3 | 3 | 6 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.08 |