| SP | Gibson, B.Gibson, Bob # >> | 33 | 1968 | R | 93 | 36 | 36 | 10 | 17 | 5.16 | .315 | 1.35 | 9.6 | 2.6 | 5.6 | 221.1 | 235 | 128 | 127 | 22 | 63 | 137 | 10 | 0 | 0 | 1 | 14 | 7 | 2 | 4.00 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 36 | 36 | 13 | 9 | 4.45 | .320 | 1.39 | 10.2 | 2.3 | 5.6 | 224.1 | 253 | 116 | 111 | 26 | 58 | 139 | 6 | 0 | 0 | 3 | 17 | 5 | 2 | 4.11 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 34 | 34 | 12 | 15 | 4.19 | .293 | 1.20 | 8.7 | 2.2 | 3.8 | 225.1 | 217 | 110 | 105 | 16 | 54 | 96 | 4 | 0 | 0 | 3 | 17 | 9 | 9 | 3.91 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 33 | 33 | 8 | 10 | 4.72 | .325 | 1.40 | 9.4 | 3.3 | 4.7 | 215.2 | 224 | 118 | 113 | 23 | 79 | 112 | 7 | 0 | 0 | 2 | 12 | 8 | 2 | 4.56 |
| RP | Chapman, A.Chapman, Aroldis >> | 26 | 2014 | L | 93 | 98 | 0 | 3 | 4 | 3.44 | .314 | 1.37 | 6.7 | 5.7 | 10.4 | 81.0 | 60 | 32 | 31 | 4 | 51 | 94 | 0 | 3 | 3 | 0 | 0 | 0 | 8 | 3.21 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 97 | 0 | 4 | 3 | 4.89 | .294 | 1.22 | 9.1 | 1.9 | 8.3 | 99.1 | 100 | 54 | 54 | 12 | 21 | 91 | 0 | 7 | 5 | 0 | 0 | 3 | 0 | 3.46 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 77 | 0 | 5 | 5 | 5.22 | .324 | 1.41 | 8.8 | 4.0 | 5.5 | 79.1 | 77 | 54 | 46 | 14 | 35 | 48 | 0 | 8 | 5 | 0 | 0 | 2 | 0 | 5.49 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 80 | 64 | 0 | 7 | 5 | 4.18 | .292 | 1.19 | 6.7 | 4.1 | 9.4 | 75.1 | 56 | 36 | 35 | 8 | 34 | 78 | 0 | 10 | 1 | 0 | 0 | 3 | 2 | 3.79 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 73 | 44 | 0 | 1 | 7 | 5.26 | .342 | 1.56 | 6.9 | 7.2 | 7.8 | 51.1 | 39 | 30 | 30 | 3 | 41 | 44 | 0 | 2 | 3 | 0 | 0 | 0 | 1 | 4.45 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 50 | 0 | 5 | 2 | 5.34 | .342 | 1.54 | 9.6 | 4.4 | 6.0 | 62.1 | 66 | 39 | 37 | 14 | 30 | 41 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 6.11 |