| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 8 | 8 | 4 | 3 | 2.97 | .231 | 0.88 | 6.0 | 2.1 | 11.5 | 57.2 | 38 | 20 | 19 | 9 | 13 | 73 | 2 | 0 | 0 | 0 | 5 | 1 | 0 | 3.23 |
| SP | Flaherty, J.Flaherty, Jack >> | 25 | 2021 | R | 93 | 8 | 8 | 0 | 7 | 8.42 | .429 | 2.23 | 13.6 | 6.4 | 8.7 | 31.0 | 47 | 31 | 29 | 8 | 22 | 30 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 6.65 |
| SP | Musgrove, J.Musgrove, Joseph >> | 28 | 2021 | R | 89 | 8 | 8 | 1 | 4 | 5.08 | .342 | 1.56 | 10.8 | 3.3 | 12.3 | 44.1 | 53 | 29 | 25 | 13 | 16 | 60 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 5.20 |
| SP | Urquidy, J.Urquidy, Jose >> | 26 | 2021 | R | 87 | 7 | 7 | 2 | 3 | 4.46 | .297 | 1.24 | 8.8 | 2.5 | 6.8 | 40.1 | 39 | 24 | 20 | 8 | 11 | 30 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 5.00 |
| SP | Montas, F.Montas, Frankie >> | 28 | 2021 | R | 76 | 7 | 7 | 3 | 3 | 4.39 | .313 | 1.34 | 8.1 | 4.0 | 11.0 | 41.0 | 37 | 20 | 20 | 6 | 18 | 50 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 3.85 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 100 | 15 | 0 | 1 | 1 | 2.35 | .258 | 1.04 | 5.4 | 4.2 | 15.0 | 15.1 | 9 | 4 | 4 | 1 | 7 | 25 | 0 | 9 | 1 | 0 | 0 | 0 | 2 | 1.93 |
| SU | Iglesias, R.Iglesias, Raisel >> | 31 | 2021 | R | 95 | 19 | 0 | 1 | 0 | 0.40 | .183 | 0.67 | 4.9 | 1.2 | 12.7 | 22.1 | 12 | 3 | 1 | 0 | 3 | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0.59 |
| RP | Rodriguez, R.Rodriguez, Richard >> | 31 | 2021 | R | 82 | 19 | 0 | 1 | 0 | 3.12 | .271 | 1.12 | 9.0 | 1.0 | 9.3 | 26.0 | 26 | 9 | 9 | 7 | 3 | 27 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.77 |
| RP | Trivino, L.Trivino, Lou >> | 29 | 2021 | R | 58 | 20 | 0 | 2 | 2 | 4.09 | .359 | 1.68 | 9.0 | 6.1 | 10.2 | 22.0 | 22 | 13 | 10 | 4 | 15 | 25 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 5.14 |
| RP | Weathers, R.Weathers, Ryan >> | 21 | 2021 | R | 27 | 13 | 0 | 0 | 0 | 4.66 | .346 | 1.55 | 11.5 | 2.5 | 6.8 | 29.0 | 37 | 15 | 15 | 5 | 8 | 22 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.66 |
| SP | Davies, Z.Davies, Zach >> | 28 | 2021 | R | 14 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Yarbrough, R.Yarbrough, Ryan >> | 29 | 2021 | L | 47 | 3 | 0 | 0 | 0 | 0.00 | .000 | 0.00 | 0.0 | 0.0 | 9.0 | 1.0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 1.00 |