| SP | Peralta, F.Peralta, Freddy # >> | 29 | 2021 | R | 99 | 28 | 28 | 10 | 12 | 3.78 | .267 | 1.06 | 7.0 | 2.5 | 10.4 | 162.0 | 126 | 70 | 68 | 18 | 45 | 188 | 1 | 0 | 0 | 1 | 16 | 6 | 2 | 3.07 |
| SP | Hurter, B.Hurter, Brant >> | 26 | 2024 | L | 92 | 28 | 28 | 10 | 10 | 4.61 | .300 | 1.24 | 8.2 | 3.0 | 8.0 | 130.2 | 118 | 76 | 67 | 24 | 44 | 115 | 0 | 0 | 0 | 0 | 5 | 6 | 0 | 4.78 |
| SP | Rogers, T.Rogers, Trevor >> | 27 | 2021 | L | 91 | 27 | 27 | 7 | 12 | 3.78 | .252 | 0.98 | 7.0 | 1.8 | 10.4 | 162.0 | 126 | 70 | 68 | 28 | 33 | 187 | 1 | 0 | 0 | 0 | 18 | 5 | 3 | 3.64 |
| SP | Skubal, T.Skubal, Tarik >> | 28 | 2024 | L | 91 | 27 | 27 | 8 | 12 | 5.68 | .305 | 1.28 | 9.1 | 2.5 | 9.4 | 142.2 | 143 | 95 | 90 | 37 | 40 | 148 | 1 | 0 | 0 | 0 | 10 | 5 | 4 | 5.25 |
| CL | Hudson, B.Hudson, Bryan † >> | 28 | 2024 | L | 97 | 45 | 0 | 3 | 3 | 1.53 | .208 | 0.72 | 4.0 | 2.5 | 8.6 | 47.0 | 21 | 8 | 8 | 3 | 13 | 45 | 0 | 30 | 1 | 0 | 0 | 3 | 0 | 2.94 |
| RP | Staumont, J.Staumont, Josh >> | 31 | 2020 | R | 85 | 61 | 0 | 4 | 1 | 3.55 | .258 | 1.03 | 5.4 | 3.9 | 10.7 | 78.2 | 47 | 31 | 31 | 8 | 34 | 93 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 3.29 |
| RP | Rondon, B.Rondon, Bruce >> | 34 | 2016 | R | 86 | 40 | 0 | 0 | 2 | 2.49 | .274 | 1.13 | 7.1 | 3.1 | 8.2 | 43.1 | 34 | 12 | 12 | 5 | 15 | 39 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.74 |
| RP | Jimenez, J.Jimenez, Joe >> | 30 | 2018 | R | 87 | 44 | 0 | 5 | 2 | 5.81 | .319 | 1.40 | 9.9 | 2.8 | 8.7 | 62.0 | 68 | 42 | 40 | 14 | 19 | 60 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 4.92 |
| SP | Fulmer, M.Fulmer, Michael >> | 32 | 2016 | R | 85 | 27 | 8 | 3 | 6 | 5.13 | .316 | 1.36 | 9.4 | 2.8 | 7.2 | 121.0 | 127 | 79 | 69 | 22 | 37 | 97 | 0 | 0 | 0 | 0 | 4 | 4 | 3 | 4.78 |