| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 12 | 12 | 4 | 6 | 2.86 | .259 | 1.04 | 7.1 | 2.2 | 9.4 | 85.0 | 67 | 28 | 27 | 9 | 21 | 89 | 1 | 0 | 0 | 1 | 8 | 1 | 2 | 3.06 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 12 | 12 | 3 | 6 | 5.68 | .300 | 1.27 | 9.5 | 2.1 | 7.2 | 77.2 | 81 | 49 | 49 | 14 | 18 | 62 | 1 | 0 | 0 | 0 | 4 | 1 | 1 | 4.49 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 12 | 12 | 3 | 5 | 4.96 | .317 | 1.38 | 9.9 | 2.5 | 5.8 | 89.0 | 98 | 51 | 49 | 9 | 25 | 57 | 2 | 0 | 0 | 0 | 4 | 1 | 3 | 3.91 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 72 | 12 | 12 | 1 | 6 | 5.13 | .354 | 1.61 | 10.4 | 4.1 | 4.3 | 79.0 | 91 | 46 | 45 | 11 | 36 | 38 | 1 | 0 | 0 | 0 | 4 | 3 | 2 | 5.33 |
| SP | Hendrix, C.Hendrix, Claude >> | 25 | 1914 | R | 69 | 13 | 11 | 3 | 3 | 6.29 | .378 | 1.81 | 11.3 | 5.2 | 5.2 | 68.2 | 85 | 58 | 48 | 10 | 39 | 39 | 0 | 0 | 0 | 0 | 4 | 1 | 2 | 5.53 |
| RP | Uehara, K.Uehara, Koji $ >> | 38 | 2013 | R | 100 | 25 | 0 | 2 | 2 | 2.67 | .254 | 1.02 | 6.9 | 2.4 | 8.1 | 30.1 | 23 | 10 | 9 | 5 | 8 | 27 | 0 | 8 | 2 | 0 | 0 | 0 | 0 | 4.17 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 35 | 0 | 3 | 4 | 3.47 | .297 | 1.24 | 5.8 | 5.5 | 6.8 | 36.1 | 23 | 17 | 14 | 4 | 22 | 27 | 0 | 2 | 2 | 0 | 0 | 1 | 1 | 4.86 |
| CL | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 27 | 0 | 2 | 4 | 5.64 | .345 | 1.58 | 10.2 | 4.2 | 6.0 | 30.1 | 34 | 19 | 19 | 4 | 14 | 20 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 4.80 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 15 | 0 | 0 | 0 | 4.05 | .302 | 1.30 | 8.6 | 3.2 | 9.9 | 20.0 | 19 | 16 | 9 | 2 | 7 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.15 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 78 | 14 | 0 | 0 | 2 | 10.22 | .413 | 2.11 | 12.0 | 7.5 | 4.5 | 12.1 | 16 | 15 | 14 | 5 | 10 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9.92 |