| SP | Johnson, W.Johnson, Walter † $ >> | 26 | 1913 | R | 95 | 27 | 27 | 12 | 11 | 3.77 | .306 | 1.28 | 9.3 | 2.2 | 5.2 | 186.1 | 192 | 96 | 78 | 18 | 46 | 108 | 7 | 0 | 0 | 2 | 17 | 8 | 3 | 3.97 |
| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 26 | 26 | 9 | 9 | 4.24 | .322 | 1.41 | 8.8 | 4.0 | 5.3 | 152.2 | 148 | 79 | 72 | 14 | 67 | 90 | 0 | 0 | 0 | 0 | 14 | 3 | 4 | 4.39 |
| SP | Santana, J.Santana, Johan # >> | 25 | 2004 | L | 86 | 26 | 26 | 9 | 9 | 4.88 | .304 | 1.30 | 9.1 | 2.7 | 8.1 | 173.1 | 174 | 104 | 94 | 28 | 52 | 155 | 3 | 0 | 0 | 1 | 11 | 1 | 5 | 4.23 |
| SP | Hunter, C.Hunter, Catfish # >> | 26 | 1972 | R | 80 | 26 | 26 | 8 | 11 | 5.55 | .334 | 1.49 | 9.7 | 3.7 | 5.4 | 167.0 | 180 | 113 | 103 | 30 | 68 | 100 | 1 | 0 | 0 | 0 | 10 | 3 | 4 | 5.41 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 76 | 26 | 26 | 10 | 6 | 4.77 | .314 | 1.34 | 9.7 | 2.4 | 5.4 | 168.0 | 181 | 98 | 89 | 26 | 44 | 100 | 5 | 0 | 0 | 0 | 13 | 6 | 5 | 4.71 |
| CL | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 58 | 0 | 6 | 7 | 3.30 | .285 | 1.18 | 8.1 | 2.6 | 10.2 | 62.2 | 56 | 24 | 23 | 10 | 18 | 70 | 0 | 26 | 7 | 0 | 0 | 1 | 3 | 3.76 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 49 | 0 | 3 | 2 | 5.68 | .319 | 1.35 | 9.2 | 3.0 | 8.5 | 57.0 | 58 | 38 | 36 | 5 | 19 | 54 | 0 | 0 | 1 | 0 | 0 | 3 | 2 | 3.40 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 44 | 0 | 2 | 2 | 5.61 | .328 | 1.36 | 9.0 | 3.4 | 7.6 | 51.1 | 51 | 36 | 32 | 9 | 19 | 43 | 0 | 1 | 1 | 0 | 0 | 5 | 0 | 5.02 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 68 | 39 | 0 | 2 | 2 | 4.58 | .288 | 1.19 | 7.4 | 3.3 | 7.4 | 57.0 | 47 | 33 | 29 | 5 | 21 | 47 | 0 | 2 | 2 | 0 | 0 | 1 | 4 | 3.65 |