| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 8 | 15 | 4.79 | .301 | 1.28 | 9.1 | 2.4 | 9.2 | 216.0 | 218 | 116 | 115 | 31 | 58 | 221 | 0 | 0 | 0 | 0 | 18 | 3 | 0 | 3.67 |
| SP | Scott, M.Scott, Mike # >> | 31 | 1986 | R | 87 | 33 | 33 | 11 | 15 | 4.98 | .318 | 1.36 | 8.8 | 3.5 | 8.6 | 227.2 | 222 | 129 | 126 | 33 | 88 | 216 | 7 | 0 | 0 | 1 | 17 | 8 | 3 | 4.26 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 63 | 31 | 31 | 11 | 10 | 4.49 | .325 | 1.42 | 9.4 | 3.5 | 3.9 | 224.2 | 233 | 116 | 112 | 20 | 87 | 96 | 5 | 0 | 0 | 0 | 16 | 5 | 4 | 4.54 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 86 | 0 | 6 | 4 | 3.34 | .283 | 1.18 | 8.5 | 2.2 | 8.8 | 113.1 | 107 | 44 | 42 | 13 | 27 | 111 | 0 | 8 | 4 | 0 | 0 | 0 | 2 | 3.25 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 73 | 0 | 7 | 7 | 2.93 | .263 | 1.07 | 7.8 | 1.8 | 7.4 | 86.0 | 75 | 34 | 28 | 13 | 17 | 71 | 0 | 9 | 3 | 0 | 0 | 0 | 0 | 3.91 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 72 | 53 | 0 | 4 | 6 | 2.75 | .304 | 1.31 | 8.0 | 3.9 | 8.3 | 55.2 | 49 | 19 | 17 | 4 | 24 | 51 | 0 | 2 | 1 | 0 | 0 | 0 | 3 | 3.40 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 2 | 2 | 1 | 1 | 7.56 | .390 | 1.92 | 12.4 | 5.6 | 10.1 | 8.1 | 11 | 8 | 7 | 1 | 5 | 9 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 4.25 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 3 | 0 | 0 | 1 | 12.00 | .471 | 2.67 | 18.0 | 6.0 | 12.0 | 3.0 | 6 | 4 | 4 | 2 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 11.00 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 56 | 24 | 0 | 1 | 5 | 5.77 | .359 | 1.66 | 10.9 | 4.1 | 5.6 | 53.0 | 64 | 38 | 34 | 6 | 24 | 33 | 0 | 2 | 1 | 0 | 0 | 1 | 4 | 4.64 |