| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 13 | 13 | 6 | 3 | 4.16 | .309 | 1.32 | 7.3 | 4.6 | 10.1 | 84.1 | 68 | 43 | 39 | 15 | 43 | 94 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 4.69 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 91 | 13 | 13 | 6 | 2 | 3.48 | .287 | 1.17 | 7.9 | 2.7 | 9.4 | 82.2 | 72 | 37 | 32 | 9 | 25 | 86 | 0 | 0 | 0 | 0 | 8 | 3 | 3 | 3.35 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 13 | 13 | 1 | 5 | 7.44 | .381 | 1.77 | 12.3 | 3.6 | 8.7 | 52.0 | 71 | 44 | 43 | 9 | 21 | 50 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 4.77 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 72 | 13 | 12 | 6 | 3 | 3.25 | .283 | 1.16 | 7.9 | 2.7 | 7.3 | 88.2 | 77 | 36 | 32 | 18 | 26 | 71 | 3 | 0 | 0 | 2 | 8 | 2 | 5 | 5.00 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 29 | 0 | 2 | 1 | 3.95 | .257 | 0.99 | 7.1 | 1.9 | 10.3 | 43.1 | 34 | 19 | 19 | 7 | 9 | 49 | 0 | 3 | 2 | 0 | 0 | 2 | 1 | 3.60 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 68 | 22 | 0 | 1 | 1 | 4.32 | .299 | 1.24 | 6.1 | 5.0 | 6.5 | 25.0 | 17 | 12 | 12 | 5 | 14 | 18 | 0 | 3 | 0 | 0 | 0 | 1 | 0 | 5.96 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 14 | 0 | 0 | 1 | 6.92 | .381 | 1.77 | 11.1 | 4.8 | 11.1 | 13.0 | 16 | 10 | 10 | 4 | 7 | 16 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 6.38 |
| SP | DeLeon, J.DeLeon, Jose >> | 29 | 1989 | R | 60 | 3 | 0 | 0 | 2 | 13.50 | .467 | 2.63 | 22.5 | 9.0 | 4.5 | 2.2 | 5 | 4 | 4 | 2 | 2 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 18.00 |