| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 13 | 13 | 2 | 9 | 5.73 | .379 | 1.82 | 11.3 | 5.0 | 7.5 | 66.0 | 83 | 56 | 42 | 13 | 37 | 55 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 5.62 |
| SP | Millwood, K.Millwood, Kevin # >> | 25 | 1999 | R | 70 | 13 | 13 | 4 | 6 | 5.63 | .333 | 1.47 | 9.0 | 4.3 | 6.8 | 72.0 | 72 | 49 | 45 | 14 | 34 | 54 | 0 | 0 | 0 | 0 | 7 | 2 | 0 | 5.53 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 65 | 12 | 12 | 4 | 7 | 4.56 | .334 | 1.45 | 10.4 | 2.6 | 6.8 | 75.0 | 87 | 46 | 38 | 9 | 22 | 57 | 1 | 0 | 0 | 1 | 5 | 4 | 0 | 4.08 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 65 | 13 | 12 | 2 | 6 | 5.75 | .370 | 1.74 | 12.3 | 3.4 | 6.0 | 72.0 | 98 | 60 | 46 | 12 | 27 | 48 | 0 | 0 | 0 | 0 | 4 | 2 | 3 | 5.04 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 34 | 0 | 5 | 2 | 3.79 | .313 | 1.36 | 10.4 | 2.0 | 11.5 | 40.1 | 46 | 21 | 17 | 5 | 9 | 51 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2.75 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 32 | 0 | 0 | 3 | 4.97 | .352 | 1.58 | 10.2 | 4.0 | 11.6 | 38.0 | 43 | 26 | 21 | 7 | 17 | 49 | 0 | 3 | 1 | 0 | 0 | 2 | 2 | 4.32 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 22 | 0 | 0 | 2 | 8.06 | .391 | 1.88 | 13.5 | 3.7 | 9.8 | 22.1 | 33 | 24 | 20 | 6 | 9 | 24 | 0 | 3 | 0 | 0 | 0 | 1 | 1 | 5.73 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 76 | 16 | 0 | 0 | 0 | 8.20 | .417 | 2.09 | 15.5 | 4.0 | 7.5 | 18.2 | 31 | 18 | 17 | 3 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 5.00 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 64 | 16 | 0 | 0 | 0 | 3.00 | .316 | 1.33 | 8.0 | 4.0 | 9.5 | 18.0 | 16 | 8 | 6 | 2 | 8 | 19 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.83 |