| SP | Hiraha, K.Hiraha, Kenji # >> | 22 | 2021 | L | 70 | 25 | 25 | 6 | 11 | 5.52 | .322 | 1.40 | 9.7 | 3.0 | 4.5 | 137.0 | 147 | 94 | 84 | 31 | 45 | 68 | 1 | 0 | 0 | 0 | 8 | 3 | 6 | 6.00 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 91 | 33 | 33 | 11 | 9 | 4.97 | .332 | 1.47 | 10.4 | 2.8 | 6.4 | 183.0 | 212 | 117 | 101 | 34 | 57 | 130 | 1 | 0 | 0 | 0 | 14 | 4 | 3 | 4.99 |
| SP | Leonard, D.Leonard, Dutch # >> | 22 | 1914 | L | 89 | 26 | 26 | 5 | 9 | 4.75 | .317 | 1.38 | 9.1 | 3.4 | 5.2 | 146.0 | 147 | 85 | 77 | 24 | 55 | 85 | 0 | 0 | 0 | 0 | 14 | 1 | 2 | 5.12 |
| SP | Perry, G.Perry, Gaylord # >> | 34 | 1972 | R | 50 | 19 | 19 | 3 | 10 | 6.36 | .349 | 1.60 | 9.4 | 5.0 | 5.2 | 104.2 | 109 | 83 | 74 | 18 | 58 | 60 | 1 | 0 | 0 | 0 | 6 | 1 | 2 | 5.80 |
| RP | Ohtani, M.Ohtani, Masako >> | 20 | 2021 | L | 92 | 51 | 0 | 5 | 1 | 4.33 | .272 | 1.11 | 6.2 | 3.8 | 6.0 | 68.2 | 47 | 33 | 33 | 7 | 29 | 45 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.34 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 80 | 86 | 0 | 3 | 3 | 4.42 | .305 | 1.31 | 7.8 | 4.1 | 9.2 | 75.1 | 65 | 43 | 37 | 14 | 34 | 77 | 0 | 2 | 2 | 0 | 0 | 0 | 6 | 4.73 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 57 | 51 | 0 | 1 | 3 | 3.88 | .332 | 1.49 | 9.2 | 4.2 | 7.9 | 51.0 | 52 | 23 | 22 | 8 | 24 | 45 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.69 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 57 | 0 | 5 | 3 | 3.97 | .292 | 1.24 | 7.6 | 3.5 | 6.1 | 59.0 | 50 | 33 | 26 | 9 | 23 | 40 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 4.80 |
| CL | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 84 | 67 | 0 | 8 | 8 | 3.47 | .268 | 1.10 | 7.8 | 2.1 | 7.3 | 70.0 | 61 | 30 | 27 | 10 | 16 | 57 | 0 | 36 | 11 | 0 | 0 | 0 | 0 | 3.91 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 47 | 28 | 1 | 4 | 4 | 5.03 | .322 | 1.41 | 10.2 | 2.4 | 5.0 | 111.0 | 126 | 74 | 62 | 23 | 30 | 62 | 0 | 0 | 0 | 0 | 0 | 2 | 3 | 5.44 |