| SP | Adams, B.Adams, Babe † >> | 37 | 1919 | R | 92 | 34 | 34 | 15 | 11 | 4.27 | .284 | 1.16 | 8.5 | 2.0 | 3.8 | 251.0 | 236 | 125 | 119 | 37 | 56 | 105 | 9 | 0 | 0 | 0 | 16 | 7 | 6 | 4.83 |
| SP | Righetti, D.Righetti, Dave >> | 23 | 1981 | L | 94 | 32 | 32 | 15 | 10 | 3.31 | .287 | 1.19 | 7.5 | 3.3 | 5.8 | 231.1 | 192 | 90 | 85 | 17 | 84 | 148 | 3 | 0 | 0 | 0 | 22 | 4 | 6 | 3.82 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 26 | 2006 | R | 100 | 65 | 0 | 0 | 5 | 4.05 | .306 | 1.28 | 8.3 | 3.3 | 9.5 | 66.2 | 61 | 31 | 30 | 8 | 24 | 70 | 0 | 4 | 4 | 0 | 0 | 3 | 0 | 3.68 |
| RP | Labine, C.Labine, Clem >> | 29 | 1955 | R | 26 | 17 | 0 | 0 | 0 | 5.40 | .382 | 1.80 | 10.5 | 6.0 | 4.5 | 18.1 | 21 | 12 | 11 | 0 | 12 | 9 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.17 |
| CL | Cordero, F.Cordero, Francisco >> | 36 | 2011 | R | 81 | 58 | 0 | 2 | 4 | 5.34 | .353 | 1.62 | 10.5 | 4.3 | 5.7 | 55.2 | 64 | 33 | 33 | 10 | 26 | 35 | 0 | 40 | 11 | 0 | 0 | 1 | 2 | 5.56 |