| SP | Gooden, D.Gooden, Dwight † >> | 21 | 1985 | R | 100 | 34 | 34 | 18 | 11 | 2.99 | .292 | 1.22 | 8.1 | 2.9 | 5.9 | 267.2 | 241 | 115 | 89 | 27 | 85 | 175 | 14 | 0 | 0 | 2 | 23 | 5 | 4 | 4.01 |
| SP | Hershiser, O.Hershiser, Orel >> | 27 | 1985 | R | 98 | 34 | 34 | 11 | 15 | 3.80 | .328 | 1.44 | 9.1 | 3.8 | 5.0 | 220.1 | 223 | 114 | 93 | 18 | 94 | 121 | 2 | 0 | 0 | 1 | 18 | 6 | 3 | 4.33 |
| SP | Tannehill, J.Tannehill, Jesse >> | 28 | 1902 | L | 79 | 20 | 20 | 7 | 9 | 4.37 | .319 | 1.40 | 11.2 | 1.4 | 5.0 | 140.0 | 174 | 90 | 68 | 15 | 22 | 77 | 0 | 0 | 0 | 0 | 10 | 1 | 0 | 3.79 |
| SP | Buehrle, M.Buehrle, Mark # >> | 22 | 2001 | L | 75 | 32 | 32 | 10 | 15 | 4.76 | .329 | 1.46 | 10.6 | 2.6 | 4.7 | 209.2 | 245 | 125 | 111 | 24 | 61 | 110 | 3 | 0 | 0 | 1 | 16 | 2 | 6 | 4.34 |
| SP | Whitney, J.Whitney, Jim # >> | 26 | 1883 | R | 70 | 29 | 29 | 7 | 14 | 5.17 | .313 | 1.35 | 10.1 | 2.1 | 4.9 | 196.2 | 221 | 134 | 113 | 26 | 45 | 107 | 4 | 0 | 0 | 0 | 12 | 3 | 10 | 4.37 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 99 | 92 | 0 | 2 | 4 | 3.74 | .303 | 1.28 | 7.8 | 3.8 | 6.4 | 91.1 | 79 | 45 | 38 | 9 | 38 | 65 | 0 | 9 | 3 | 0 | 0 | 2 | 0 | 4.18 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 91 | 99 | 0 | 1 | 2 | 2.84 | .288 | 1.19 | 7.2 | 3.5 | 5.3 | 66.2 | 53 | 26 | 21 | 5 | 26 | 39 | 0 | 4 | 2 | 0 | 0 | 2 | 3 | 4.08 |
| RP | Andersen, L.Andersen, Larry >> | 39 | 1992 | R | 88 | 35 | 0 | 2 | 1 | 2.15 | .294 | 1.22 | 9.2 | 1.9 | 10.0 | 37.2 | 38 | 9 | 9 | 3 | 8 | 41 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 2.57 |
| RP | Quisenberry, D.Quisenberry, Dan >> | 29 | 1982 | R | 60 | 14 | 0 | 0 | 1 | 5.40 | .261 | 1.06 | 8.6 | 1.3 | 4.7 | 21.2 | 20 | 13 | 13 | 4 | 3 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.86 |
| SP | Pappas, M.Pappas, Milt >> | 24 | 1963 | R | 45 | 16 | 13 | 3 | 8 | 5.89 | .371 | 1.77 | 11.0 | 5.1 | 4.9 | 73.1 | 89 | 50 | 48 | 11 | 41 | 40 | 0 | 0 | 0 | 0 | 4 | 0 | 4 | 5.55 |