| SP | Skubal, T.Skubal, Tarik $$ >> | 28 | 2025 | L | 100 | 28 | 28 | 10 | 9 | 3.40 | .271 | 1.07 | 7.2 | 2.4 | 9.9 | 185.1 | 149 | 72 | 70 | 29 | 49 | 203 | 0 | 0 | 0 | 0 | 19 | 9 | 2 | 3.78 |
| SP | Crochet, G.Crochet, Garrett >> | 26 | 2025 | L | 89 | 27 | 27 | 13 | 7 | 4.18 | .319 | 1.36 | 9.6 | 2.6 | 10.8 | 170.0 | 182 | 80 | 79 | 24 | 49 | 204 | 0 | 0 | 0 | 0 | 15 | 8 | 3 | 3.44 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 81 | 27 | 27 | 9 | 5 | 4.72 | .314 | 1.34 | 9.1 | 3.1 | 7.3 | 131.2 | 132 | 69 | 69 | 24 | 45 | 106 | 0 | 0 | 0 | 0 | 4 | 4 | 3 | 4.89 |
| SP | Valdez, F.Valdez, Framber >> | 31 | 2025 | L | 64 | 26 | 25 | 9 | 10 | 5.00 | .338 | 1.50 | 9.3 | 4.2 | 6.6 | 144.0 | 149 | 84 | 80 | 26 | 67 | 105 | 0 | 0 | 0 | 0 | 14 | 5 | 4 | 5.39 |
| RP | Pomeranz, D.Pomeranz, Drew >> | 36 | 2025 | L | 71 | 65 | 0 | 6 | 2 | 1.92 | .239 | 0.90 | 5.7 | 2.5 | 11.2 | 79.2 | 50 | 18 | 17 | 3 | 22 | 98 | 0 | 1 | 4 | 0 | 0 | 3 | 2 | 1.96 |
| RP | Sterner, J.Sterner, Justin >> | 28 | 2025 | R | 78 | 61 | 0 | 11 | 1 | 4.84 | .338 | 1.48 | 8.3 | 5.2 | 10.2 | 61.1 | 56 | 34 | 33 | 8 | 35 | 69 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 4.31 |
| RP | Brubaker, J.Brubaker, JT >> | 31 | 2025 | R | 42 | 54 | 0 | 1 | 4 | 3.84 | .322 | 1.40 | 8.6 | 4.0 | 7.0 | 68.0 | 65 | 31 | 29 | 5 | 30 | 53 | 0 | 1 | 0 | 0 | 0 | 2 | 6 | 3.81 |
| CL | Miller, M.Miller, Mason >> | 26 | 2025 | R | 98 | 56 | 0 | 1 | 7 | 3.98 | .293 | 1.20 | 6.2 | 4.6 | 10.2 | 61.0 | 42 | 27 | 27 | 6 | 31 | 69 | 0 | 24 | 6 | 0 | 0 | 3 | 4 | 3.69 |
| SU | Suarez, R.Suarez, Robert >> | 34 | 2025 | R | 91 | 55 | 0 | 1 | 0 | 3.22 | .298 | 1.26 | 7.9 | 3.5 | 10.8 | 64.1 | 56 | 24 | 23 | 7 | 25 | 77 | 0 | 5 | 3 | 0 | 0 | 1 | 0 | 3.23 |