| RP | Duchscherer, J.Duchscherer, Justin + >> | 29 | 2006 | R | 93 | 73 | 0 | 2 | 5 | 3.57 | .276 | 1.09 | 8.3 | 1.5 | 6.9 | 88.1 | 81 | 36 | 35 | 11 | 15 | 67 | 0 | 3 | 5 | 0 | 0 | 5 | 1 | 3.78 |
| RP | Bradford, C.Bradford, Chad >> | 32 | 2006 | R | 86 | 72 | 0 | 8 | 2 | 3.52 | .297 | 1.20 | 8.9 | 1.9 | 6.0 | 84.1 | 83 | 37 | 33 | 7 | 18 | 56 | 0 | 7 | 3 | 0 | 0 | 6 | 0 | 3.61 |
| SP | Maine, J.Maine, John + >> | 25 | 2006 | R | 99 | 40 | 40 | 12 | 12 | 3.70 | .294 | 1.23 | 8.1 | 3.0 | 6.0 | 243.0 | 218 | 107 | 100 | 19 | 81 | 163 | 1 | 0 | 0 | 0 | 23 | 5 | 2 | 3.74 |
| RP | Thornton, M.Thornton, Matt >> | 30 | 2006 | L | 90 | 134 | 0 | 8 | 6 | 5.28 | .339 | 1.51 | 9.1 | 4.5 | 6.4 | 122.2 | 124 | 79 | 72 | 21 | 61 | 87 | 0 | 3 | 5 | 0 | 0 | 4 | 1 | 5.41 |
| RP | Proctor, S.Proctor, Scott >> | 29 | 2006 | R | 91 | 112 | 0 | 3 | 9 | 4.04 | .333 | 1.48 | 9.2 | 4.1 | 6.5 | 124.2 | 127 | 65 | 56 | 14 | 57 | 89 | 0 | 11 | 2 | 0 | 0 | 3 | 4 | 4.48 |
| RP | Heilman, A.Heilman, Aaron >> | 28 | 2006 | R | 95 | 94 | 0 | 5 | 3 | 3.69 | .296 | 1.22 | 7.3 | 3.8 | 5.4 | 109.2 | 88 | 45 | 45 | 12 | 46 | 66 | 0 | 3 | 6 | 0 | 0 | 4 | 5 | 4.60 |
| SP | Johnson, R.Johnson, Randy >> | 43 | 2006 | L | 90 | 40 | 40 | 6 | 19 | 5.83 | .343 | 1.51 | 10.3 | 3.4 | 7.7 | 219.1 | 250 | 154 | 142 | 34 | 82 | 187 | 1 | 0 | 0 | 0 | 12 | 11 | 6 | 4.58 |
| SP | Arroyo, B.Arroyo, Bronson + >> | 29 | 2006 | R | 94 | 34 | 29 | 9 | 14 | 4.56 | .321 | 1.37 | 9.7 | 2.6 | 5.2 | 211.1 | 228 | 115 | 107 | 21 | 61 | 121 | 4 | 0 | 0 | 0 | 17 | 11 | 11 | 4.17 |
| RP | Carrasco, H.Carrasco, Hector >> | 37 | 2006 | R | 85 | 52 | 0 | 4 | 4 | 3.07 | .274 | 1.13 | 7.8 | 2.5 | 5.9 | 73.1 | 63 | 29 | 25 | 5 | 20 | 48 | 0 | 6 | 0 | 0 | 0 | 0 | 1 | 3.40 |
| SP | Santana, E.Santana, Ervin >> | 23 | 2006 | R | 91 | 40 | 40 | 9 | 19 | 5.44 | .334 | 1.46 | 9.0 | 4.2 | 6.4 | 221.2 | 221 | 140 | 134 | 37 | 103 | 158 | 1 | 0 | 0 | 0 | 16 | 10 | 10 | 5.28 |