| SP | Pettitte, A.Pettitte, Andy >> | 32 | 2004 | L | 96 | 57 | 57 | 22 | 6 | 3.55 | .304 | 1.28 | 8.0 | 3.6 | 7.6 | 319.2 | 283 | 136 | 126 | 32 | 126 | 268 | 0 | 0 | 0 | 0 | 27 | 9 | 11 | 3.89 |
| SP | Greinke, Z.Greinke, Zack >> | 21 | 2004 | R | 91 | 57 | 57 | 19 | 19 | 4.87 | .312 | 1.33 | 9.8 | 2.2 | 6.7 | 351.1 | 382 | 203 | 190 | 61 | 87 | 260 | 3 | 0 | 0 | 2 | 30 | 9 | 5 | 4.60 |
| SP | Escobar, K.Escobar, Kelvim >> | 28 | 2004 | R | 89 | 56 | 56 | 15 | 22 | 5.22 | .353 | 1.62 | 10.3 | 4.3 | 7.1 | 310.1 | 356 | 198 | 180 | 42 | 147 | 245 | 1 | 0 | 0 | 0 | 20 | 5 | 18 | 4.65 |
| RP | Aquino, G.Aquino, Greg >> | 26 | 2004 | R | 96 | 141 | 0 | 10 | 3 | 3.96 | .289 | 1.20 | 7.3 | 3.6 | 6.6 | 181.2 | 146 | 84 | 80 | 28 | 72 | 133 | 0 | 6 | 8 | 0 | 0 | 4 | 9 | 4.80 |
| RP | Marte, D.Marte, Damaso >> | 29 | 2004 | L | 94 | 138 | 0 | 4 | 6 | 3.54 | .301 | 1.27 | 6.8 | 4.6 | 7.1 | 150.0 | 114 | 63 | 59 | 16 | 77 | 118 | 0 | 4 | 4 | 0 | 0 | 3 | 2 | 4.41 |
| RP | Shouse, B.Shouse, Brian >> | 36 | 2004 | L | 91 | 154 | 0 | 5 | 9 | 2.79 | .281 | 1.15 | 7.3 | 3.1 | 6.1 | 167.2 | 135 | 61 | 52 | 16 | 58 | 114 | 0 | 8 | 6 | 0 | 0 | 4 | 0 | 3.99 |
| RP | Tavarez, J.Tavarez, Julian >> | 31 | 2004 | R | 89 | 99 | 0 | 6 | 5 | 4.35 | .290 | 1.20 | 8.0 | 2.8 | 5.3 | 93.0 | 83 | 47 | 45 | 11 | 29 | 55 | 0 | 19 | 4 | 0 | 0 | 2 | 1 | 4.35 |
| RP | Romero, J.Romero, J.C. >> | 28 | 2004 | L | 88 | 125 | 0 | 6 | 4 | 2.77 | .287 | 1.19 | 6.7 | 4.0 | 6.8 | 117.0 | 87 | 43 | 36 | 9 | 52 | 89 | 0 | 9 | 3 | 0 | 0 | 2 | 5 | 3.86 |
| RP | Worrell, T.Worrell, Tim >> | 37 | 2004 | R | 87 | 125 | 0 | 10 | 3 | 3.78 | .318 | 1.36 | 9.5 | 2.9 | 6.2 | 116.2 | 122 | 50 | 49 | 7 | 37 | 80 | 0 | 6 | 3 | 0 | 0 | 4 | 0 | 3.47 |
| RP | Duchscherer, J.Duchscherer, Justin >> | 27 | 2004 | R | 85 | 63 | 0 | 4 | 5 | 3.35 | .282 | 1.17 | 7.5 | 3.0 | 6.2 | 78.0 | 65 | 30 | 29 | 12 | 26 | 54 | 0 | 8 | 1 | 0 | 0 | 1 | 2 | 4.65 |