| SP | Martinez, P.Martinez, Pedro + >> | 34 | 2005 | R | 100 | 20 | 20 | 8 | 7 | 3.31 | .290 | 1.16 | 7.3 | 3.1 | 6.2 | 147.0 | 120 | 64 | 54 | 13 | 51 | 102 | 4 | 0 | 0 | 1 | 12 | 9 | 2 | 3.99 |
| SP | Clemens, R.Clemens, Roger + >> | 43 | 2005 | R | 99 | 20 | 20 | 12 | 4 | 2.96 | .293 | 1.23 | 7.7 | 3.4 | 5.8 | 137.0 | 117 | 50 | 45 | 4 | 52 | 89 | 2 | 0 | 0 | 1 | 12 | 1 | 6 | 3.24 |
| SP | Hernandez, F.Hernandez, Felix + >> | 19 | 2005 | R | 100 | 21 | 21 | 7 | 9 | 3.79 | .306 | 1.30 | 8.6 | 3.2 | 6.5 | 145.0 | 138 | 66 | 61 | 19 | 51 | 105 | 4 | 0 | 0 | 2 | 14 | 3 | 5 | 4.37 |
| SP | Halladay, R.Halladay, Roy + >> | 28 | 2005 | R | 97 | 20 | 20 | 7 | 9 | 4.68 | .340 | 1.51 | 10.5 | 3.1 | 6.0 | 142.1 | 166 | 84 | 74 | 23 | 49 | 95 | 4 | 0 | 0 | 1 | 10 | 5 | 3 | 4.91 |
| RP | Politte, C.Politte, Cliff + >> | 31 | 2005 | R | 100 | 51 | 0 | 3 | 2 | 2.57 | .215 | 0.82 | 4.7 | 2.7 | 6.8 | 56.0 | 29 | 17 | 16 | 3 | 17 | 42 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 3.11 |
| RP | Street, H.Street, Huston + >> | 22 | 2005 | R | 100 | 41 | 0 | 3 | 5 | 4.39 | .313 | 1.34 | 9.2 | 2.9 | 5.7 | 41.0 | 42 | 21 | 20 | 4 | 13 | 26 | 0 | 15 | 3 | 0 | 0 | 1 | 1 | 4.02 |
| RP | Speier, J.Speier, Justin + >> | 32 | 2005 | R | 99 | 28 | 0 | 2 | 1 | 2.53 | .289 | 1.17 | 8.6 | 2.1 | 7.7 | 21.1 | 20 | 9 | 6 | 2 | 5 | 18 | 0 | 2 | 1 | 0 | 0 | 1 | 1 | 3.38 |
| RP | Fultz, A.Fultz, Aaron + >> | 32 | 2005 | L | 98 | 41 | 0 | 1 | 1 | 2.64 | .258 | 1.01 | 6.0 | 3.3 | 5.7 | 30.2 | 20 | 12 | 9 | 2 | 11 | 19 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.80 |
| RP | Hensley, C.Hensley, Clay + >> | 26 | 2005 | R | 93 | 55 | 0 | 4 | 2 | 2.19 | .274 | 1.11 | 7.1 | 3.0 | 5.9 | 102.2 | 80 | 27 | 25 | 6 | 34 | 67 | 0 | 3 | 3 | 0 | 0 | 2 | 2 | 3.51 |
| SP | Maholm, P.Maholm, Paul + >> | 23 | 2005 | L | 91 | 21 | 21 | 14 | 3 | 3.54 | .311 | 1.33 | 7.9 | 4.1 | 5.2 | 145.0 | 127 | 59 | 57 | 7 | 66 | 83 | 2 | 0 | 0 | 0 | 14 | 3 | 0 | 3.91 |
| SP | Sheets, B.Sheets, Ben + >> | 27 | 2005 | R | 94 | 21 | 21 | 9 | 7 | 3.56 | .303 | 1.28 | 8.8 | 2.7 | 5.8 | 134.0 | 131 | 58 | 53 | 15 | 40 | 87 | 1 | 0 | 0 | 0 | 15 | 4 | 6 | 4.14 |