| SP | Verlander, J.Verlander, Justin >> | 28 | 2011 | R | 94 | 35 | 35 | 16 | 11 | 4.15 | .314 | 1.35 | 8.7 | 3.4 | 7.3 | 267.0 | 258 | 133 | 123 | 33 | 102 | 218 | 10 | 0 | 0 | 2 | 20 | 6 | 8 | 4.19 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 82 | 35 | 35 | 9 | 12 | 5.17 | .353 | 1.61 | 10.6 | 3.9 | 9.0 | 224.2 | 264 | 143 | 129 | 28 | 98 | 224 | 1 | 0 | 0 | 1 | 19 | 6 | 2 | 4.02 |
| SP | Skubal, T.Skubal, Tarik >> | 27 | 2024 | L | 89 | 33 | 33 | 16 | 9 | 3.98 | .300 | 1.25 | 8.7 | 2.6 | 10.0 | 210.1 | 202 | 98 | 93 | 28 | 60 | 233 | 0 | 0 | 0 | 0 | 23 | 8 | 4 | 3.49 |
| SP | Rodriguez, E.Rodriguez, Eduardo # >> | 30 | 2023 | L | 41 | 33 | 33 | 9 | 10 | 5.90 | .324 | 1.41 | 10.1 | 2.6 | 7.5 | 183.0 | 205 | 130 | 120 | 36 | 53 | 153 | 0 | 0 | 0 | 0 | 15 | 5 | 2 | 4.84 |
| SP | Lolich, M.Lolich, Mickey >> | 24 | 1964 | L | 43 | 31 | 30 | 7 | 6 | 5.59 | .352 | 1.59 | 11.1 | 3.3 | 6.3 | 164.1 | 202 | 105 | 102 | 24 | 60 | 114 | 0 | 0 | 0 | 0 | 7 | 6 | 1 | 4.72 |
| RP | Alburquerque, A.Alburquerque, Al >> | 25 | 2011 | R | 60 | 88 | 0 | 4 | 6 | 2.83 | .328 | 1.45 | 6.1 | 7.0 | 9.4 | 108.0 | 73 | 42 | 34 | 3 | 84 | 113 | 0 | 6 | 3 | 0 | 0 | 1 | 9 | 3.63 |
| RP | Greene, S.Greene, Shane >> | 30 | 2019 | R | 83 | 84 | 0 | 8 | 9 | 5.09 | .322 | 1.40 | 7.8 | 4.8 | 7.6 | 99.0 | 86 | 60 | 56 | 11 | 53 | 84 | 0 | 7 | 10 | 0 | 0 | 2 | 0 | 4.41 |
| RP | Hurter, B.Hurter, Brant >> | 25 | 2024 | L | 51 | 76 | 0 | 10 | 8 | 3.88 | .293 | 1.22 | 8.5 | 2.6 | 6.2 | 116.0 | 109 | 52 | 50 | 15 | 33 | 80 | 0 | 11 | 9 | 0 | 0 | 2 | 0 | 4.21 |
| RP | Saucier, K.Saucier, Kevin >> | 25 | 1981 | L | 64 | 47 | 0 | 2 | 5 | 4.82 | .341 | 1.50 | 9.0 | 4.5 | 6.1 | 56.0 | 56 | 32 | 30 | 6 | 28 | 38 | 0 | 4 | 2 | 0 | 0 | 3 | 3 | 4.70 |
| RP | Wilson, J.Wilson, Justin >> | 29 | 2017 | L | 73 | 38 | 0 | 1 | 0 | 3.43 | .296 | 1.26 | 7.1 | 4.3 | 10.1 | 42.0 | 33 | 16 | 16 | 6 | 20 | 47 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 4.05 |
| RP | Zachary, C.Zachary, Chris >> | 28 | 1972 | R | 38 | 43 | 0 | 3 | 5 | 4.99 | .323 | 1.36 | 8.5 | 3.8 | 7.4 | 52.1 | 49 | 29 | 29 | 8 | 22 | 43 | 0 | 3 | 1 | 0 | 0 | 4 | 0 | 4.85 |