| SP | Lamet, D.Lamet, Dinelson >> | 27 | 2020 | R | 98 | 11 | 11 | 0 | 1 | 3.00 | .308 | 1.33 | 7.0 | 5.0 | 8.7 | 27.0 | 21 | 9 | 9 | 2 | 15 | 26 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.70 |
| SP | Pivetta, N.Pivetta, Nick # >> | 32 | 2025 | R | 71 | 13 | 13 | 7 | 4 | 3.73 | .281 | 1.16 | 8.6 | 1.9 | 7.6 | 82.0 | 78 | 34 | 34 | 8 | 17 | 69 | 0 | 0 | 0 | 0 | 7 | 1 | 2 | 3.24 |
| SP | Darvish, Y.Darvish, Yu >> | 35 | 2022 | R | 74 | 12 | 12 | 4 | 2 | 4.03 | .285 | 1.18 | 8.6 | 2.1 | 8.0 | 80.1 | 76 | 36 | 36 | 11 | 19 | 71 | 1 | 0 | 0 | 1 | 8 | 1 | 1 | 3.76 |
| SP | Paddack, C.Paddack, Chris >> | 23 | 2019 | R | 66 | 12 | 12 | 3 | 6 | 7.67 | .365 | 1.67 | 11.2 | 3.8 | 7.7 | 54.0 | 67 | 48 | 46 | 14 | 23 | 46 | 0 | 0 | 0 | 0 | 4 | 3 | 0 | 6.11 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 99 | 33 | 0 | 1 | 0 | 1.62 | .184 | 0.68 | 3.7 | 2.5 | 8.2 | 44.1 | 18 | 8 | 8 | 5 | 12 | 40 | 0 | 5 | 2 | 0 | 0 | 0 | 1 | 3.48 |
| RP | Benoit, J.Benoit, Joaquin >> | 37 | 2014 | R | 94 | 25 | 0 | 0 | 1 | 2.54 | .309 | 1.34 | 5.8 | 6.4 | 8.0 | 28.1 | 18 | 8 | 8 | 3 | 20 | 25 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 4.75 |
| RP | Thatcher, J.Thatcher, Joe >> | 29 | 2010 | L | 76 | 16 | 0 | 2 | 3 | 2.25 | .191 | 0.71 | 5.3 | 1.1 | 9.0 | 24.0 | 14 | 6 | 6 | 1 | 3 | 24 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 1.92 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 81 | 13 | 0 | 3 | 1 | 4.96 | .269 | 1.10 | 8.4 | 1.7 | 9.6 | 16.1 | 15 | 9 | 9 | 4 | 3 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.69 |
| RP | Castillo, J.Castillo, Jose >> | 22 | 2018 | L | 75 | 11 | 0 | 1 | 0 | 1.54 | .255 | 0.94 | 4.1 | 4.9 | 10.6 | 11.2 | 5 | 2 | 2 | 2 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.91 |
| SP | Pomeranz, D.Pomeranz, Drew >> | 27 | 2016 | L | 72 | 14 | 2 | 4 | 3 | 4.19 | .324 | 1.41 | 7.8 | 4.9 | 6.7 | 73.0 | 63 | 35 | 34 | 5 | 40 | 54 | 0 | 0 | 0 | 0 | 1 | 2 | 1 | 4.14 |