| SP | Verlander, J.Verlander, Justin † >> | 39 | 2022 | R | 100 | 35 | 35 | 18 | 7 | 3.57 | .281 | 1.16 | 8.2 | 2.2 | 8.5 | 234.1 | 214 | 96 | 93 | 18 | 57 | 221 | 3 | 0 | 0 | 2 | 20 | 4 | 5 | 2.89 |
| SP | Richard, J.Richard, J.R. † # >> | 30 | 1980 | R | 99 | 34 | 34 | 18 | 9 | 4.00 | .289 | 1.21 | 7.6 | 3.3 | 8.0 | 236.1 | 199 | 106 | 105 | 14 | 86 | 211 | 1 | 0 | 0 | 0 | 21 | 3 | 4 | 3.11 |
| SP | Javier, C.Javier, Cristian >> | 25 | 2022 | R | 98 | 33 | 33 | 16 | 7 | 3.81 | .303 | 1.27 | 7.5 | 3.9 | 9.4 | 174.2 | 145 | 77 | 74 | 12 | 76 | 182 | 0 | 0 | 0 | 0 | 12 | 7 | 5 | 3.24 |
| SP | Urquidy, J.Urquidy, Jose # >> | 26 | 2021 | R | 71 | 32 | 32 | 10 | 6 | 5.10 | .319 | 1.40 | 9.7 | 2.9 | 6.4 | 169.1 | 183 | 102 | 96 | 29 | 54 | 121 | 0 | 0 | 0 | 0 | 12 | 1 | 2 | 4.78 |
| SP | McHugh, C.McHugh, Collin >> | 27 | 2014 | R | 74 | 32 | 31 | 11 | 8 | 4.97 | .332 | 1.47 | 9.7 | 3.5 | 7.5 | 186.1 | 201 | 108 | 103 | 19 | 72 | 155 | 3 | 0 | 0 | 2 | 14 | 5 | 2 | 3.90 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 96 | 67 | 0 | 5 | 5 | 3.06 | .280 | 1.17 | 6.4 | 4.2 | 11.0 | 67.2 | 48 | 30 | 23 | 8 | 31 | 82 | 0 | 43 | 6 | 0 | 0 | 0 | 0 | 3.49 |
| RP | Okert, S.Okert, Steven >> | 33 | 2025 | L | 59 | 69 | 0 | 3 | 4 | 2.03 | .292 | 1.22 | 6.5 | 4.6 | 10.0 | 53.1 | 38 | 14 | 12 | 3 | 27 | 59 | 0 | 6 | 1 | 0 | 0 | 1 | 0 | 3.09 |
| RP | Pressly, R.Pressly, Ryan >> | 33 | 2022 | R | 65 | 99 | 0 | 6 | 2 | 2.61 | .292 | 1.22 | 7.3 | 3.8 | 9.1 | 79.1 | 64 | 25 | 23 | 6 | 33 | 80 | 0 | 1 | 3 | 0 | 0 | 1 | 0 | 3.25 |
| RP | Osuna, R.Osuna, Roberto >> | 24 | 2019 | R | 61 | 71 | 0 | 5 | 2 | 2.80 | .274 | 1.07 | 6.9 | 2.7 | 9.1 | 61.0 | 47 | 19 | 19 | 6 | 18 | 62 | 0 | 3 | 6 | 0 | 0 | 4 | 3 | 3.33 |
| RP | Blubaugh, A.Blubaugh, AJ >> | 24 | 2025 | R | 75 | 40 | 0 | 5 | 2 | 3.42 | .339 | 1.49 | 7.1 | 6.3 | 8.0 | 71.0 | 56 | 27 | 27 | 6 | 50 | 63 | 0 | 2 | 2 | 0 | 0 | 3 | 0 | 4.56 |