| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 31 | 31 | 11 | 11 | 3.36 | .293 | 1.23 | 7.9 | 3.1 | 8.8 | 228.0 | 201 | 91 | 85 | 16 | 79 | 223 | 2 | 0 | 0 | 1 | 21 | 4 | 4 | 3.05 |
| SP | Mathewson, C.Mathewson, Christy † >> | 29 | 1909 | R | 86 | 33 | 33 | 17 | 9 | 2.90 | .272 | 1.10 | 7.8 | 2.1 | 4.3 | 267.1 | 232 | 99 | 86 | 19 | 63 | 129 | 13 | 0 | 0 | 4 | 22 | 5 | 0 | 3.72 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 84 | 32 | 32 | 17 | 10 | 3.37 | .282 | 1.18 | 7.9 | 2.8 | 3.5 | 248.2 | 217 | 96 | 93 | 18 | 76 | 97 | 9 | 0 | 0 | 4 | 16 | 0 | 4 | 4.08 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 70 | 32 | 32 | 14 | 13 | 4.85 | .332 | 1.48 | 9.7 | 3.6 | 5.3 | 235.2 | 254 | 137 | 127 | 26 | 95 | 139 | 10 | 0 | 0 | 2 | 13 | 2 | 8 | 4.49 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 68 | 32 | 32 | 8 | 18 | 5.07 | .330 | 1.46 | 9.0 | 4.1 | 5.4 | 213.0 | 213 | 126 | 120 | 21 | 97 | 128 | 4 | 0 | 0 | 0 | 16 | 5 | 6 | 4.52 |
| RP | Betances, D.Betances, Dellin >> | 26 | 2014 | R | 94 | 87 | 0 | 6 | 6 | 2.64 | .258 | 1.03 | 5.5 | 3.8 | 8.6 | 102.1 | 62 | 30 | 30 | 4 | 43 | 97 | 0 | 10 | 4 | 0 | 0 | 2 | 1 | 2.93 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 92 | 61 | 0 | 7 | 7 | 2.93 | .271 | 1.10 | 6.9 | 3.1 | 8.0 | 70.2 | 54 | 25 | 23 | 6 | 24 | 62 | 0 | 8 | 0 | 0 | 0 | 1 | 0 | 3.41 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 78 | 30 | 0 | 1 | 2 | 3.62 | .292 | 1.24 | 7.6 | 3.7 | 6.2 | 32.1 | 27 | 16 | 13 | 4 | 13 | 22 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 4.47 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 17 | 0 | 1 | 1 | 3.93 | .321 | 1.42 | 10.5 | 2.5 | 9.0 | 18.1 | 21 | 8 | 8 | 3 | 5 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.00 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 2 | 2 | 1 | 1 | 1.69 | .273 | 1.13 | 6.3 | 4.5 | 10.8 | 10.2 | 7 | 3 | 2 | 1 | 5 | 12 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.40 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 57 | 4 | 0 | 0 | 0 | 3.00 | .280 | 1.17 | 10.5 | 0.0 | 7.5 | 6.0 | 7 | 2 | 2 | 1 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |