| SP | Plesac, Z.Plesac, Zach + >> | 25 | 2020 | R | 95 | 36 | 36 | 11 | 10 | 4.20 | .296 | 1.23 | 9.0 | 2.0 | 8.9 | 193.0 | 194 | 94 | 90 | 32 | 43 | 190 | 3 | 0 | 0 | 0 | 15 | 7 | 0 | 3.96 |
| SP | Wacha, M.Wacha, Michael >> | 28 | 2014 | R | 90 | 33 | 33 | 14 | 9 | 3.58 | .276 | 1.13 | 8.1 | 2.0 | 6.8 | 219.0 | 198 | 101 | 87 | 28 | 49 | 166 | 5 | 0 | 0 | 2 | 21 | 3 | 2 | 3.86 |
| SP | Hendricks, K.Hendricks, Kyle # >> | 30 | 2016 | R | 85 | 33 | 33 | 14 | 12 | 3.49 | .276 | 1.11 | 7.7 | 2.3 | 7.1 | 204.0 | 175 | 85 | 79 | 23 | 52 | 161 | 5 | 0 | 0 | 3 | 17 | 6 | 5 | 3.74 |
| SP | Faria, J.Faria, Jake # >> | 26 | 2017 | R | 82 | 17 | 17 | 3 | 4 | 5.43 | .337 | 1.51 | 9.4 | 4.3 | 9.3 | 69.2 | 72 | 43 | 42 | 11 | 33 | 71 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 4.49 |
| RP | De La Rosa, R.De La Rosa, Rubby >> | 31 | 2011 | R | 87 | 75 | 0 | 13 | 10 | 3.95 | .284 | 1.15 | 8.0 | 2.4 | 9.5 | 155.0 | 137 | 72 | 68 | 23 | 42 | 163 | 0 | 4 | 5 | 0 | 0 | 5 | 2 | 3.74 |
| RP | Ramirez, N.Ramirez, Neil >> | 31 | 2014 | R | 88 | 59 | 0 | 6 | 3 | 3.67 | .320 | 1.41 | 8.9 | 3.9 | 10.4 | 73.2 | 72 | 35 | 30 | 13 | 32 | 84 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 4.33 |
| CL | Edwards, C.Edwards, Carl † >> | 28 | 2016 | R | 100 | 67 | 0 | 3 | 1 | 3.66 | .267 | 1.05 | 6.8 | 2.7 | 10.4 | 71.1 | 54 | 30 | 29 | 5 | 21 | 82 | 0 | 43 | 7 | 0 | 0 | 3 | 6 | 2.62 |
| RP | Kahnle, T.Kahnle, Tommy # >> | 30 | 2014 | R | 80 | 46 | 0 | 7 | 3 | 4.85 | .310 | 1.30 | 8.2 | 3.5 | 8.4 | 59.1 | 54 | 33 | 32 | 9 | 23 | 55 | 0 | 1 | 4 | 0 | 0 | 3 | 4 | 4.44 |
| RP | Kolarek, A.Kolarek, Adam >> | 31 | 2020 | L | 80 | 38 | 0 | 4 | 0 | 2.28 | .257 | 1.01 | 6.3 | 2.9 | 5.4 | 47.1 | 33 | 12 | 12 | 4 | 15 | 28 | 0 | 3 | 0 | 0 | 0 | 1 | 6 | 3.94 |
| SP | Arrieta, J.Arrieta, Jake # >> | 34 | 2015 | R | 85 | 32 | 0 | 7 | 9 | 4.88 | .320 | 1.39 | 8.8 | 3.7 | 7.5 | 149.1 | 146 | 84 | 81 | 24 | 62 | 124 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 4.74 |
| SP | Richards, G.Richards, Garrett >> | 32 | 2014 | R | 83 | 24 | 14 | 4 | 4 | 4.74 | .321 | 1.42 | 9.3 | 3.5 | 9.2 | 79.2 | 82 | 44 | 42 | 9 | 31 | 81 | 0 | 1 | 0 | 0 | 6 | 0 | 8 | 3.61 |