| SP | Rodriguez, E.Rodriguez, Eduardo # >> | 29 | 2015 | L | 70 | 11 | 11 | 5 | 4 | 5.40 | .299 | 1.28 | 9.3 | 2.3 | 8.3 | 63.1 | 65 | 40 | 38 | 14 | 16 | 58 | 1 | 0 | 0 | 1 | 4 | 0 | 2 | 4.81 |
| SP | Chirinos, Y.Chirinos, Yonny # >> | 28 | 2019 | R | 70 | 11 | 11 | 4 | 4 | 5.16 | .315 | 1.38 | 10.7 | 1.8 | 9.0 | 59.1 | 70 | 36 | 34 | 14 | 12 | 59 | 1 | 0 | 0 | 0 | 4 | 0 | 0 | 4.69 |
| SP | Quintana, J.Quintana, Jose >> | 33 | 2012 | L | 28 | 11 | 11 | 3 | 4 | 3.48 | .293 | 1.23 | 8.6 | 2.5 | 8.7 | 62.0 | 59 | 25 | 24 | 10 | 17 | 60 | 1 | 0 | 0 | 0 | 7 | 1 | 2 | 4.03 |
| SP | Masterson, J.Masterson, Justin >> | 37 | 2008 | R | 23 | 11 | 11 | 2 | 5 | 5.36 | .365 | 1.66 | 10.9 | 4.0 | 8.8 | 47.0 | 57 | 33 | 28 | 11 | 21 | 46 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 5.62 |
| CL | Anderson, N.Anderson, Nick >> | 31 | 2020 | R | 100 | 15 | 0 | 1 | 0 | 1.15 | .203 | 0.77 | 4.8 | 2.4 | 12.6 | 15.2 | 8 | 2 | 2 | 2 | 4 | 21 | 0 | 12 | 0 | 0 | 0 | 0 | 0 | 2.73 |
| RP | Houck, T.Houck, Tanner + >> | 26 | 2020 | R | 93 | 22 | 0 | 4 | 0 | 2.95 | .262 | 1.05 | 4.7 | 4.7 | 10.3 | 61.0 | 32 | 20 | 20 | 9 | 32 | 70 | 0 | 3 | 1 | 0 | 0 | 1 | 3 | 4.25 |
| RP | Hutchison, D.Hutchison, Drew >> | 31 | 2012 | R | 75 | 22 | 0 | 4 | 0 | 4.89 | .307 | 1.33 | 8.8 | 3.1 | 10.0 | 46.0 | 45 | 25 | 25 | 10 | 16 | 51 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 4.65 |
| RP | Herrera, K.Herrera, Kelvin >> | 32 | 2014 | R | 67 | 14 | 0 | 1 | 2 | 3.97 | .346 | 1.54 | 10.2 | 4.1 | 9.4 | 22.2 | 25 | 12 | 10 | 5 | 10 | 23 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.36 |
| RP | Brasier, R.Brasier, Ryan >> | 34 | 2018 | R | 62 | 10 | 0 | 3 | 1 | 5.40 | .318 | 1.30 | 10.8 | 0.9 | 7.2 | 10.0 | 12 | 6 | 6 | 3 | 1 | 8 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5.90 |
| RP | Kahnle, T.Kahnle, Tommy >> | 32 | 2014 | R | 78 | 7 | 0 | 1 | 0 | 2.61 | .225 | 0.87 | 6.3 | 1.8 | 13.5 | 10.1 | 7 | 3 | 3 | 2 | 2 | 15 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 3.20 |
| RP | Schreiber, J.Schreiber, John >> | 28 | 2022 | R | 52 | 13 | 0 | 2 | 1 | 4.42 | .304 | 1.20 | 7.5 | 3.5 | 11.0 | 18.1 | 15 | 10 | 9 | 4 | 7 | 22 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 4.94 |