| SP | Arrieta, J.Arrieta, Jake † >> | 29 | 2015 | R | 96 | 32 | 32 | 19 | 7 | 3.39 | .289 | 1.22 | 8.2 | 2.7 | 8.9 | 207.0 | 189 | 84 | 78 | 19 | 63 | 204 | 2 | 0 | 0 | 0 | 23 | 1 | 6 | 3.15 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 31 | 31 | 13 | 12 | 4.20 | .331 | 1.48 | 8.2 | 5.1 | 4.5 | 182.1 | 166 | 93 | 85 | 13 | 103 | 90 | 0 | 0 | 0 | 0 | 17 | 2 | 6 | 4.67 |
| SP | Prior, M.Prior, Mark # >> | 22 | 2002 | R | 43 | 32 | 31 | 11 | 12 | 5.96 | .349 | 1.56 | 9.9 | 4.1 | 8.4 | 157.0 | 173 | 108 | 104 | 24 | 72 | 146 | 0 | 0 | 0 | 0 | 13 | 7 | 3 | 4.64 |
| SP | Alexander, P.Alexander, Pete # >> | 32 | 1919 | R | 60 | 30 | 28 | 12 | 8 | 4.86 | .344 | 1.55 | 11.2 | 2.8 | 5.7 | 179.2 | 222 | 108 | 97 | 19 | 56 | 113 | 6 | 0 | 0 | 0 | 14 | 5 | 7 | 4.14 |
| CL | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 93 | 58 | 0 | 0 | 3 | 3.30 | .268 | 1.10 | 6.8 | 3.2 | 7.7 | 57.1 | 43 | 21 | 21 | 4 | 20 | 49 | 0 | 37 | 3 | 0 | 0 | 0 | 2 | 3.25 |
| SU | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 99 | 51 | 0 | 2 | 1 | 2.90 | .304 | 1.31 | 7.0 | 5.0 | 8.4 | 49.2 | 38 | 16 | 16 | 3 | 27 | 46 | 0 | 6 | 3 | 0 | 0 | 0 | 2 | 3.57 |
| RP | Leiter, M.Leiter, Mark >> | 33 | 2024 | R | 39 | 65 | 0 | 0 | 5 | 5.30 | .337 | 1.51 | 9.1 | 4.6 | 8.8 | 74.2 | 75 | 44 | 44 | 10 | 38 | 72 | 0 | 1 | 0 | 0 | 0 | 1 | 4 | 4.39 |
| RP | Weaver, H.Weaver, Harry >> | 26 | 1918 | R | 32 | 50 | 0 | 3 | 5 | 3.13 | .299 | 1.27 | 7.3 | 4.1 | 3.8 | 89.0 | 72 | 34 | 31 | 7 | 41 | 38 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4.58 |
| RP | Grimm, J.Grimm, Justin >> | 28 | 2017 | R | 17 | 49 | 0 | 3 | 2 | 6.95 | .377 | 1.80 | 11.0 | 5.4 | 7.5 | 55.2 | 67 | 44 | 43 | 10 | 33 | 46 | 0 | 0 | 1 | 0 | 0 | 1 | 4 | 5.55 |
| RP | Rondon, H.Rondon, Hector >> | 28 | 2016 | R | 44 | 54 | 0 | 5 | 3 | 5.31 | .338 | 1.53 | 11.8 | 2.2 | 8.4 | 62.2 | 81 | 37 | 37 | 11 | 15 | 58 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 4.16 |