| SP | Verlander, J.Verlander, Justin >> | 39 | 2022 | R | 100 | 25 | 25 | 14 | 9 | 3.55 | .290 | 1.23 | 8.6 | 2.5 | 8.7 | 157.1 | 150 | 70 | 62 | 15 | 43 | 151 | 0 | 0 | 0 | 0 | 16 | 0 | 1 | 3.14 |
| SP | Javier, C.Javier, Cristian >> | 25 | 2022 | R | 100 | 25 | 25 | 8 | 10 | 2.82 | .277 | 1.12 | 7.5 | 2.6 | 8.1 | 140.2 | 117 | 44 | 44 | 5 | 41 | 126 | 0 | 0 | 0 | 0 | 11 | 4 | 5 | 2.63 |
| SP | Garcia, L.Garcia, Luis >> | 25 | 2022 | R | 86 | 24 | 24 | 10 | 4 | 3.15 | .280 | 1.13 | 8.0 | 2.2 | 8.2 | 145.2 | 129 | 51 | 51 | 9 | 35 | 132 | 0 | 0 | 0 | 0 | 13 | 6 | 5 | 2.83 |
| SP | Valdez, F.Valdez, Framber >> | 28 | 2022 | L | 82 | 23 | 23 | 7 | 11 | 4.75 | .335 | 1.50 | 10.2 | 3.3 | 7.6 | 138.1 | 157 | 73 | 73 | 20 | 50 | 117 | 0 | 0 | 0 | 0 | 11 | 2 | 2 | 4.32 |
| SP | Urquidy, J.Urquidy, Jose >> | 27 | 2022 | R | 68 | 18 | 18 | 5 | 5 | 6.00 | .348 | 1.56 | 9.8 | 4.2 | 5.9 | 96.0 | 105 | 68 | 64 | 16 | 45 | 63 | 0 | 0 | 0 | 0 | 7 | 4 | 1 | 5.39 |
| RP | Neris, H.Neris, Hector >> | 33 | 2022 | R | 93 | 68 | 0 | 4 | 3 | 3.29 | .261 | 1.06 | 7.2 | 2.3 | 10.0 | 82.0 | 66 | 31 | 30 | 8 | 21 | 91 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 2.82 |
| CL | Pressly, R.Pressly, Ryan >> | 33 | 2022 | R | 99 | 51 | 0 | 3 | 5 | 3.57 | .329 | 1.45 | 8.8 | 4.2 | 10.7 | 53.0 | 52 | 21 | 21 | 6 | 25 | 63 | 0 | 27 | 6 | 0 | 0 | 1 | 0 | 3.57 |
| RP | Montero, R.Montero, Rafael >> | 31 | 2022 | R | 94 | 53 | 0 | 0 | 1 | 2.28 | .239 | 0.94 | 6.4 | 2.1 | 10.1 | 59.1 | 42 | 15 | 15 | 4 | 14 | 66 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 2.36 |
| RP | Martinez, S.Martinez, Seth >> | 27 | 2022 | R | 91 | 29 | 0 | 0 | 2 | 2.79 | .254 | 1.02 | 6.4 | 2.8 | 11.4 | 42.0 | 30 | 13 | 13 | 4 | 13 | 53 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.64 |
| RP | Brown, H.Brown, Hunter >> | 23 | 2022 | R | 86 | 27 | 0 | 3 | 3 | 3.67 | .293 | 1.20 | 7.2 | 3.7 | 9.0 | 49.0 | 39 | 22 | 20 | 4 | 20 | 49 | 0 | 1 | 3 | 0 | 0 | 2 | 0 | 3.41 |
| SP | McCullers, L.McCullers, Lance >> | 29 | 2022 | R | 74 | 19 | 0 | 2 | 1 | 3.42 | .313 | 1.37 | 9.1 | 3.2 | 9.0 | 79.0 | 80 | 30 | 30 | 6 | 28 | 79 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.05 |