| SP | Verlander, J.Verlander, Justin >> | 39 | 2022 | R | 100 | 32 | 32 | 14 | 11 | 3.28 | .262 | 1.05 | 7.3 | 2.2 | 9.6 | 216.2 | 174 | 81 | 79 | 25 | 53 | 230 | 1 | 0 | 0 | 1 | 19 | 4 | 5 | 3.17 |
| SP | Javier, C.Javier, Cristian >> | 25 | 2022 | R | 99 | 32 | 32 | 14 | 10 | 2.32 | .243 | 0.92 | 5.6 | 2.7 | 10.3 | 182.0 | 113 | 56 | 47 | 11 | 55 | 208 | 2 | 0 | 0 | 2 | 15 | 7 | 3 | 2.52 |
| SP | Garcia, L.Garcia, Luis >> | 25 | 2022 | R | 82 | 31 | 31 | 9 | 11 | 4.12 | .282 | 1.16 | 7.3 | 3.1 | 9.4 | 181.1 | 147 | 85 | 83 | 34 | 63 | 189 | 1 | 0 | 0 | 0 | 14 | 4 | 6 | 4.46 |
| SP | Valdez, F.Valdez, Framber >> | 28 | 2022 | L | 78 | 29 | 29 | 8 | 15 | 4.72 | .292 | 1.21 | 8.6 | 2.3 | 7.6 | 183.0 | 174 | 99 | 96 | 31 | 47 | 154 | 1 | 0 | 0 | 0 | 13 | 5 | 8 | 4.37 |
| SP | Urquidy, J.Urquidy, Jose >> | 27 | 2022 | R | 65 | 24 | 24 | 11 | 9 | 4.79 | .322 | 1.40 | 9.7 | 2.9 | 6.5 | 135.1 | 146 | 73 | 72 | 14 | 43 | 98 | 0 | 0 | 0 | 0 | 13 | 4 | 3 | 3.94 |
| RP | Neris, H.Neris, Hector >> | 33 | 2022 | R | 88 | 78 | 0 | 1 | 3 | 2.91 | .263 | 1.05 | 7.0 | 2.5 | 10.3 | 105.1 | 82 | 35 | 34 | 11 | 29 | 120 | 0 | 1 | 4 | 0 | 0 | 2 | 2 | 2.96 |
| CL | Pressly, R.Pressly, Ryan >> | 33 | 2022 | R | 97 | 63 | 0 | 2 | 5 | 1.38 | .207 | 0.75 | 5.0 | 1.8 | 9.3 | 65.0 | 36 | 11 | 10 | 4 | 13 | 67 | 0 | 44 | 1 | 0 | 0 | 2 | 0 | 2.43 |
| RP | Montero, R.Montero, Rafael >> | 31 | 2022 | R | 90 | 70 | 0 | 2 | 4 | 2.57 | .274 | 1.09 | 6.3 | 3.5 | 9.0 | 77.0 | 54 | 25 | 22 | 4 | 30 | 77 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 2.96 |
| RP | Martinez, S.Martinez, Seth >> | 27 | 2022 | R | 86 | 46 | 0 | 3 | 2 | 1.87 | .228 | 0.89 | 5.3 | 2.7 | 9.0 | 53.0 | 31 | 11 | 11 | 3 | 16 | 53 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.64 |
| RP | Brown, H.Brown, Hunter >> | 23 | 2022 | R | 79 | 25 | 0 | 1 | 5 | 3.67 | .264 | 0.99 | 5.8 | 3.2 | 9.8 | 34.1 | 22 | 14 | 14 | 2 | 12 | 37 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 2.91 |
| SP | McCullers, L.McCullers, Lance >> | 29 | 2022 | R | 71 | 24 | 0 | 1 | 5 | 4.28 | .308 | 1.30 | 7.8 | 3.9 | 8.6 | 101.0 | 87 | 48 | 48 | 12 | 44 | 96 | 0 | 0 | 1 | 0 | 0 | 4 | 6 | 4.07 |