| SP | Verlander, J.Verlander, Justin >> | 39 | 2022 | R | 99 | 35 | 35 | 15 | 12 | 3.35 | .264 | 1.06 | 7.3 | 2.3 | 9.7 | 236.1 | 191 | 90 | 88 | 28 | 59 | 255 | 1 | 0 | 0 | 1 | 21 | 4 | 5 | 3.18 |
| SP | Javier, C.Javier, Cristian >> | 25 | 2022 | R | 98 | 35 | 35 | 16 | 11 | 2.32 | .246 | 0.94 | 5.6 | 2.8 | 10.5 | 198.0 | 124 | 60 | 51 | 11 | 62 | 231 | 2 | 0 | 0 | 2 | 15 | 8 | 4 | 2.45 |
| SP | Garcia, L.Garcia, Luis >> | 25 | 2022 | R | 80 | 34 | 34 | 11 | 12 | 3.83 | .279 | 1.13 | 7.1 | 3.1 | 9.1 | 202.0 | 160 | 90 | 86 | 34 | 69 | 204 | 1 | 0 | 0 | 0 | 17 | 5 | 7 | 4.27 |
| SP | Valdez, F.Valdez, Framber >> | 28 | 2022 | L | 75 | 33 | 33 | 12 | 15 | 4.16 | .279 | 1.12 | 7.9 | 2.1 | 7.4 | 214.0 | 189 | 102 | 99 | 32 | 51 | 177 | 1 | 0 | 0 | 0 | 17 | 8 | 8 | 4.12 |
| SP | Urquidy, J.Urquidy, Jose >> | 27 | 2022 | R | 63 | 26 | 26 | 11 | 10 | 4.82 | .321 | 1.39 | 9.8 | 2.8 | 6.7 | 143.2 | 156 | 79 | 77 | 17 | 44 | 106 | 0 | 0 | 0 | 0 | 14 | 4 | 3 | 4.07 |
| RP | Neris, H.Neris, Hector >> | 33 | 2022 | R | 86 | 85 | 0 | 1 | 3 | 2.90 | .267 | 1.07 | 7.2 | 2.5 | 10.2 | 114.2 | 91 | 38 | 37 | 11 | 32 | 129 | 0 | 1 | 4 | 0 | 0 | 2 | 3 | 2.89 |
| CL | Pressly, R.Pressly, Ryan >> | 33 | 2022 | R | 96 | 69 | 0 | 2 | 5 | 1.51 | .213 | 0.79 | 5.2 | 1.9 | 10.0 | 71.1 | 41 | 13 | 12 | 5 | 15 | 79 | 0 | 49 | 1 | 0 | 0 | 2 | 0 | 2.41 |
| RP | Montero, R.Montero, Rafael >> | 31 | 2022 | R | 87 | 77 | 0 | 2 | 4 | 2.45 | .267 | 1.06 | 6.1 | 3.4 | 9.6 | 84.1 | 57 | 26 | 23 | 5 | 32 | 90 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 2.88 |
| RP | Martinez, S.Martinez, Seth >> | 27 | 2022 | R | 84 | 49 | 0 | 4 | 3 | 2.08 | .232 | 0.91 | 5.3 | 2.9 | 9.5 | 56.1 | 33 | 13 | 13 | 3 | 18 | 59 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 2.55 |
| RP | Brown, H.Brown, Hunter >> | 23 | 2022 | R | 77 | 26 | 0 | 1 | 5 | 3.57 | .264 | 0.99 | 5.9 | 3.1 | 9.5 | 35.1 | 23 | 14 | 14 | 2 | 12 | 37 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 2.91 |
| SP | McCullers, L.McCullers, Lance >> | 29 | 2022 | R | 70 | 26 | 0 | 1 | 5 | 4.11 | .306 | 1.29 | 8.0 | 3.6 | 8.9 | 111.2 | 99 | 51 | 51 | 13 | 45 | 110 | 0 | 0 | 1 | 0 | 0 | 4 | 7 | 3.86 |