| SP | Peralta, F.Peralta, Freddy >> | 25 | 2021 | R | 98 | 36 | 36 | 10 | 8 | 2.37 | .254 | 0.99 | 5.6 | 3.2 | 10.0 | 209.0 | 131 | 57 | 55 | 13 | 75 | 232 | 0 | 0 | 0 | 0 | 21 | 8 | 3 | 2.78 |
| SP | Burnes, C.Burnes, Corbin >> | 26 | 2021 | R | 97 | 35 | 35 | 15 | 12 | 3.01 | .265 | 1.07 | 7.4 | 2.3 | 10.6 | 224.1 | 185 | 76 | 75 | 19 | 56 | 263 | 0 | 0 | 0 | 0 | 23 | 2 | 3 | 2.53 |
| SP | Woodruff, B.Woodruff, Brandon >> | 28 | 2021 | R | 95 | 35 | 35 | 12 | 14 | 3.42 | .278 | 1.14 | 7.9 | 2.4 | 10.3 | 223.2 | 195 | 85 | 85 | 24 | 59 | 254 | 2 | 0 | 0 | 0 | 22 | 4 | 3 | 2.97 |
| SP | Anderson, B.Anderson, Brett >> | 33 | 2021 | L | 20 | 26 | 25 | 5 | 8 | 3.86 | .303 | 1.27 | 8.6 | 2.8 | 5.7 | 114.1 | 109 | 50 | 49 | 14 | 36 | 72 | 0 | 0 | 0 | 0 | 1 | 4 | 0 | 4.39 |
| RP | Richards, T.Richards, Trevor >> | 28 | 2021 | R | 93 | 91 | 0 | 11 | 4 | 3.07 | .273 | 1.11 | 6.9 | 3.1 | 9.3 | 135.0 | 103 | 47 | 46 | 11 | 47 | 140 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | 3.07 |
| RP | Boxberger, B.Boxberger, Brad >> | 33 | 2021 | R | 85 | 91 | 0 | 6 | 1 | 3.02 | .259 | 1.02 | 6.4 | 2.9 | 10.1 | 113.1 | 80 | 38 | 38 | 9 | 36 | 127 | 0 | 1 | 3 | 0 | 0 | 3 | 1 | 2.82 |
| RP | Cousins, J.Cousins, Jake >> | 26 | 2021 | R | 82 | 72 | 0 | 3 | 2 | 2.45 | .261 | 1.05 | 5.3 | 4.1 | 10.0 | 88.0 | 52 | 25 | 24 | 11 | 40 | 98 | 0 | 3 | 4 | 0 | 0 | 1 | 3 | 3.80 |
| RP | Williams, D.Williams, Devin >> | 26 | 2021 | R | 75 | 53 | 0 | 5 | 2 | 1.91 | .267 | 1.06 | 5.9 | 3.7 | 10.1 | 56.2 | 37 | 13 | 12 | 3 | 23 | 63 | 0 | 3 | 0 | 0 | 0 | 2 | 3 | 2.79 |
| RP | Rasmussen, D.Rasmussen, Drew >> | 25 | 2021 | R | 77 | 27 | 0 | 6 | 3 | 1.35 | .281 | 1.05 | 6.8 | 2.7 | 6.5 | 33.1 | 25 | 6 | 5 | 0 | 10 | 24 | 0 | 1 | 0 | 0 | 0 | 4 | 1 | 2.82 |
| RP | Strickland, H.Strickland, Hunter >> | 32 | 2021 | R | 65 | 11 | 0 | 1 | 1 | 2.19 | .213 | 0.73 | 3.8 | 3.0 | 12.0 | 12.1 | 5 | 3 | 3 | 0 | 4 | 16 | 0 | 1 | 0 | 0 | 0 | 1 | 0 | 1.58 |