| SP | Chacin, J.Chacin, Jhoulys >> | 22 | 2010 | R | 36 | 25 | 25 | 8 | 10 | 3.78 | .301 | 1.27 | 7.4 | 4.1 | 8.4 | 123.2 | 101 | 64 | 52 | 18 | 56 | 115 | 0 | 0 | 0 | 0 | 9 | 3 | 4 | 4.47 |
| SP | Marquez, G.Marquez, German # >> | 23 | 2018 | R | 39 | 34 | 34 | 13 | 11 | 4.46 | .311 | 1.34 | 9.2 | 2.9 | 9.6 | 187.2 | 191 | 94 | 93 | 28 | 60 | 199 | 0 | 0 | 0 | 0 | 21 | 3 | 3 | 3.83 |
| SP | Thomson, J.Thomson, John # >> | 29 | 2002 | R | 16 | 33 | 33 | 7 | 12 | 5.56 | .328 | 1.45 | 11.0 | 2.1 | 5.2 | 183.0 | 223 | 113 | 113 | 43 | 43 | 105 | 2 | 0 | 0 | 1 | 13 | 2 | 0 | 5.64 |
| SP | Anderson, T.Anderson, Tyler >> | 28 | 2018 | L | 27 | 10 | 7 | 3 | 2 | 5.40 | .331 | 1.49 | 9.0 | 4.4 | 6.7 | 35.0 | 35 | 21 | 21 | 6 | 17 | 26 | 0 | 1 | 0 | 0 | 3 | 0 | 0 | 5.20 |
| RP | Street, H.Street, Huston >> | 26 | 2009 | R | 78 | 83 | 0 | 10 | 2 | 3.25 | .264 | 1.05 | 7.6 | 1.8 | 8.7 | 108.0 | 91 | 39 | 39 | 13 | 22 | 104 | 0 | 2 | 1 | 0 | 0 | 3 | 0 | 3.33 |
| RP | Ottavino, A.Ottavino, Adam >> | 32 | 2018 | R | 84 | 65 | 0 | 6 | 3 | 3.06 | .264 | 1.08 | 5.7 | 4.0 | 9.1 | 88.1 | 56 | 31 | 30 | 11 | 39 | 89 | 0 | 5 | 3 | 0 | 0 | 0 | 4 | 3.93 |
| RP | Miller, J.Miller, Justin >> | 28 | 2015 | R | 78 | 87 | 0 | 8 | 4 | 3.54 | .266 | 1.08 | 6.0 | 3.7 | 9.9 | 117.0 | 78 | 47 | 46 | 11 | 48 | 129 | 0 | 0 | 2 | 0 | 0 | 1 | 5 | 3.27 |
| RP | Lopez, J.Lopez, Javier >> | 26 | 2003 | L | 28 | 11 | 0 | 1 | 0 | 1.35 | .298 | 1.28 | 11.1 | 0.7 | 7.6 | 13.1 | 16 | 3 | 2 | 0 | 1 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1.54 |
| SP | Freeland, K.Freeland, Kyle >> | 31 | 2024 | L | 6 | 26 | 24 | 6 | 6 | 5.94 | .349 | 1.58 | 10.3 | 4.1 | 5.5 | 122.2 | 139 | 83 | 81 | 22 | 55 | 74 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 5.56 |
| RP | Mears, N.Mears, Nick # >> | 27 | 2024 | R | 13 | 34 | 0 | 3 | 0 | 5.36 | .376 | 1.79 | 9.5 | 6.8 | 7.0 | 40.1 | 42 | 24 | 24 | 6 | 30 | 31 | 0 | 0 | 1 | 0 | 0 | 1 | 2 | 5.73 |
| RP | Kinley, T.Kinley, Tyler >> | 33 | 2024 | R | 16 | 31 | 0 | 1 | 0 | 3.56 | .364 | 1.71 | 7.8 | 7.8 | 9.3 | 30.1 | 26 | 12 | 12 | 0 | 26 | 31 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 3.53 |