| SP | Skubal, T.Skubal, Tarik >> | 27 | 2024 | L | 93 | 36 | 36 | 21 | 8 | 3.19 | .277 | 1.12 | 8.0 | 2.1 | 8.8 | 254.0 | 227 | 94 | 90 | 28 | 58 | 249 | 1 | 0 | 0 | 0 | 23 | 7 | 3 | 3.24 |
| SP | Scherzer, M.Scherzer, Max >> | 29 | 2013 | R | 87 | 36 | 36 | 19 | 8 | 3.88 | .319 | 1.39 | 8.9 | 3.6 | 8.2 | 248.0 | 246 | 116 | 107 | 28 | 99 | 225 | 2 | 0 | 0 | 0 | 21 | 3 | 8 | 3.89 |
| SP | Verlander, J.Verlander, Justin # >> | 33 | 2016 | R | 80 | 36 | 36 | 15 | 10 | 4.29 | .300 | 1.27 | 8.8 | 2.7 | 8.8 | 249.2 | 243 | 124 | 119 | 37 | 75 | 243 | 2 | 0 | 0 | 1 | 21 | 3 | 2 | 3.92 |
| SP | Flaherty, J.Flaherty, Jack # >> | 28 | 2024 | R | 85 | 35 | 35 | 12 | 9 | 4.54 | .317 | 1.36 | 9.6 | 2.7 | 9.2 | 218.0 | 232 | 112 | 110 | 37 | 65 | 223 | 1 | 0 | 0 | 0 | 15 | 6 | 6 | 4.14 |
| SP | Olson, R.Olson, Reese # >> | 23 | 2023 | R | 57 | 35 | 35 | 11 | 5 | 4.57 | .333 | 1.48 | 9.3 | 4.0 | 8.6 | 179.1 | 185 | 94 | 91 | 27 | 80 | 172 | 0 | 0 | 0 | 0 | 7 | 3 | 3 | 4.43 |
| CL | Rondon, B.Rondon, Bruce † >> | 25 | 2016 | R | 79 | 82 | 0 | 7 | 7 | 2.54 | .227 | 0.87 | 5.2 | 2.6 | 9.2 | 85.0 | 49 | 25 | 24 | 8 | 25 | 87 | 0 | 47 | 6 | 0 | 0 | 1 | 0 | 3.09 |
| RP | Miller, S.Miller, Shelby >> | 33 | 2024 | R | 67 | 96 | 0 | 10 | 4 | 3.11 | .283 | 1.17 | 8.4 | 2.1 | 6.0 | 127.1 | 119 | 45 | 44 | 15 | 30 | 84 | 0 | 3 | 5 | 0 | 0 | 2 | 3 | 3.97 |
| RP | Podres, J.Podres, Johnny >> | 35 | 1967 | L | 45 | 2 | 0 | 1 | 0 | 4.91 | .313 | 1.36 | 15.0 | 0.0 | 0.0 | 3.2 | 5 | 2 | 2 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 7.33 |
| RP | Heinkel, D.Heinkel, Don >> | 29 | 1988 | R | 48 | 55 | 0 | 1 | 2 | 3.50 | .296 | 1.24 | 7.1 | 4.0 | 5.6 | 72.0 | 57 | 31 | 28 | 7 | 32 | 45 | 0 | 4 | 0 | 0 | 0 | 2 | 6 | 4.43 |
| RP | Jimenez, J.Jimenez, Joe >> | 27 | 2022 | R | 55 | 63 | 0 | 8 | 2 | 3.82 | .325 | 1.37 | 10.2 | 2.3 | 9.6 | 70.2 | 79 | 30 | 30 | 9 | 18 | 75 | 0 | 0 | 5 | 0 | 0 | 5 | 0 | 3.51 |